New liquid crystalline 3-methyl-6-(4-substituted phenyl)-4,5-dihydrobenzo [d] isoxazoles and 3,5-disubstituted 4,5-dihydroisoxazoles: synthesis and mesomorphic properties

Polyfunctional intermediates for the preparation of liquid-crystalline and anisotropic materials

“…The following catalytic hydrogenation of the cyclohex-2-enones (I) in the presence of 10% palladium on charcoal and potassium hydroxide in isopropanol or THF-isopropanol mixture leads to the appropriate trans-2,5-disubstituted cyclohexanones (II) (Scheme 2) [16]. The 1,3-dipolar cycloaddition of nitrile oxides to 1-alkenes or 4-substituted styrenes in the presence of N-chlorosuccinimide and triethylamine has proved to be an useful strategy for the preparation of 3,5-disubstitiuted 2-isoxazolines (III) and substituted cyclohex-2-enonyl 2-isoxazo-lines (IV) (Scheme 3) [22].…”

Prospects of the Development of New Approaches of the Preparation of Anisotropic Compounds and Materials

“…The 1,3-dipolar cycloaddition of nitrile oxides to 1-alkenes or 4-substituted styrenes in the presence of N-chlorosuccinimide and triethylamine has proved to be an useful strategy for the preparation of 3,5-disubstitiuted 2-isoxazolines (V) and substituted cyclohex-2-enonyl-2-isoxazolines (VI) [27,28] (Scheme 4). intermediates for the preparation of various anisotropic and liquid-crystalline compounds with different combinations of cyclic, bridge, terminal fragments and lateral substituents, which are in turn useful components for liquid crystalline mixtures for display and other practical applications.…”

“…22 August 2015 New Approaches of the Preparation of Anisotropic Compounds and Materials [613]/147products of their transformations were prepared according to published methods[17][18][19][20][21][22][23][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44].…”

Synthesis of new liquid crystalline isoxazole‐, pyrazole‐ and 2‐isoxazoline‐containing compounds

“…Recently the synthesis and properties of 2-isoxazoline-containing liquid crystals were reported [20][21][22]. Several of these compounds are 2-isoxazolines with 3-aryl and 5-alkyl substitutients [20].…”