New Method for Isolation of Naringin Compound from <i>Citrus maxima</i>

Abstract

This research aims to know the proper isolation method to isolate naringin compound from Citrus maxima for natural product chemistry laboratory. This natural product chemistry laboratory provides students with the essential skills and knowledge required to perform the extraction, isolation, and structural identification. The isolation began with sample preparation, extraction with methanol, partition with n-hexane, purification by crystallization using isopropanol, by analyzing the purity with Thin Layer Chromatography (TLC) tested, and the presence of functional groups with Fourier Transform Infrared (FT-IR) spectrophotometer test. The result of FT-IR spectrophotometer analysis contains hydroxy group (−OH), aromatic cyclic groups (C=C), CH 2 , CH 3 , and ether groups.

Evaluating the anti-neuropathic effects of naringin-loaded chitosan nanocarriers in a murine model of constriction injury

“…These FTIR results indicate entire matching with the naringin structure, consistent with previous investigations. 43,44 In addition, the spectrum of chitosan NPs (Figure 2(b)) presents distinctive absorption peaks at 1068, 1238, 1431 and 1637 cm -1 , indicating C-O stretching, C-N stretching, C-H bending, and N-H bending vibrational frequencies, respectively. The peaks at 2937, 3387, and 3562 cm -1 also appeared, matching C-H stretching, −OH and −NH 2 stretching bonds in the chitosan structure.…”

“…These FTIR results indicate entire matching with the naringin structure, consistent with previous investigations. 43,44 In addition, the spectrum of chitosan respectively. The peaks at 2937, 3387, and 3562 cm -1 also appeared, matching C-H stretching, −OH and −NH 2 stretching bonds in the chitosan structure.…”

Effect of ecofriendly grapefruit peel extract on PVC thin films photostabilizing tested under harmful weathering conditions

“…The presence of functional groups in the compound's structure strongly suggests that it is naringin. 16…”

“…Scheme 1 displays the structure of naringin, which is consistent with the results of the IR spectrum analysis. The presence of functional groups in the compound's structure strongly suggests that it is naringin 16 …”

Design and Development of a Self-nanoemulsifying Drug Delivery System for Co-delivery of Curcumin and Naringin for Improved Wound Healing Activity in an Animal Model

“…The absorption peak at 1043 cm−1 is linked to the anesthetic group's C-O-C bonds. These infrared spectrum data indicate that the investigated substance comprises anesthetic groups as well as a hydroxy group (OH), aromatic cyclic groups (C=C), CH2, and CH3 [36]. The C=O stretching at 1628.6 cm−1 and a characteristic peak of the hydroxyl…”