2017
DOI: 10.1055/s-0043-119865
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New Results on Brain Stimulation in Chronic Pain

Abstract: Chronic pain induces a change of the anatomical pain network, primarily comprising DLPFC, M1, somatosensory cortex, the anterior cingulate cortex, and the thalamus. In patients with chronic back pain, a progressive decrease in neocortical gray matter (DLPFC) of 5-11 % compared to healthy subjects is observed over the years [8]. Per pain year the loss of gray matter density was approximately 1.3 cm 3 .

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Cited by 6 publications
(3 citation statements)
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“…In the latter, about one-third, half the patients experienced some kind of pain relief. This phenomenon is well observed in studies involving neuromodulation in the treatment of pain 59,60 . Some studies have also observed a reduction of anxiety in volunteers allocated to placebo group 61 , an effect also observed in the present study.…”
Section: Discussionmentioning
confidence: 52%
“…In the latter, about one-third, half the patients experienced some kind of pain relief. This phenomenon is well observed in studies involving neuromodulation in the treatment of pain 59,60 . Some studies have also observed a reduction of anxiety in volunteers allocated to placebo group 61 , an effect also observed in the present study.…”
Section: Discussionmentioning
confidence: 52%
“…TES can be classified based on the current form to transcranial alternating current stimulation (tACS), transcranial direct current stimulation (tDCS), and transcranial random noise stimulation (tRNS). The technique has applications to different neurological and psychiatric disorders such as stroke [2,3], depression [4,5], epilepsy [6,7] and chronic pain [8,9]. TES applies weak currents in the range of 1-2 mA via at least two electrodes to change the brain activity level.…”
Section: Introductionmentioning
confidence: 99%
“…A maior parte dos estudos com TECNIs apresentavam apenas uma única sessão de ETCC em desenhos não clínicos. Desta forma, os dados eram muito limitados em termos de segurança cognitiva após múltiplas sessões de ETCC em contextos clínicos (85).…”
Section: Implicações Clínicasunclassified