“…Third, ultrasound imaging techniques are cost-effective imaging modalities (particularly when compared to CT and MRI methods) and can be used for frequent follow-ups. Finally, ultrasound imaging techniques can be implemented in small, portable devices that can be used for bone assessment 'in the field' where other techniques cannot be readily available, such as space-related, sports and military medicine applications (Diaz et al 2008, Kaufman et al 2007, Kirkpatrick et al 2003, McNeil et al 2009. Additionally, in recent years, the deployment of new technologies, efficient transducer materials, and advanced signal and image processing techniques have lead to diagnostic systems capable of producing ultrasound images of significantly improved image quality, high resolution 3D and 4D visualization of tissue structures (Turan et al 2009, Wang 2008) and accurate estimation of new tissue properties related to the tissue mechanical behavior (Insana et al 2004, Liu and Ebbini 2008, Righetti et al 2005, Zhai et al 2008.…”