New tetrazoloquinolinyl methoxyphenyl-4-thiazolidinones: synthesis and antihyperglycemic evaluation

Deshmukh, A. R. A. S.; Bhosle, Manisha R.; Khillare, Lalit D.; Dhumal, Sambhaji T.; Mishra, Akansha; Srivastava, Arvind K.; Mane, Ramrao A.

doi:10.1007/s11164-016-2686-5

Cited by 17 publications

(8 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4-Thiazolidinone has been considered a magic moiety because it shows a large number of biological activities such as antimicrobial, antituberculosis, antiviral, antiinflammatory, antidiabetic, anticancer, anticonvulsant, FSH agonist, and CFTR inhibitor. A large amount of literature is available for the anti-inflammatory activity [57][58][59], anticancer [60,61], antitumor [62][63][64], anticonvulsant [65][66][67], and antidiabetic activity [65,68,69]. However, in this review, we have discussed in detail about certain other biological activities related to this moiety, and these include antimicrobial (and the various targets identified), FSH agonist, CFTR inhibition, antioxidant, antiviral (various pathogens), and antituberculosis (with various targets).…”

Section: Biological Activities Of 4-thiazolidinonesmentioning

confidence: 99%

Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

Nirwan

Chahal

Kakkar

2019

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Thiazolidinone is a biologically important five‐membered heterocyclic ring having almost all types of biological activities. This review covers various types of thiazolidinones, such as 2‐thiazolidinones, 4‐thiazolidinones, 5‐thiazolidinones, 2‐thioxo‐4‐thiazolidinones, and thiazolidiene‐2,4‐dione. The literature related to the physical properties, chemical reactions, and synthesis for these derivatives has been included. Recent advances in the biological activities reported for 4‐thiazolidinone derivatives, such as peroxisome proliferator‐activated receptor γ binders, follicle‐stimulating hormone agonists, cystic fibrosis transmembrane conductance regulator inhibitors, and antioxidants, have been covered in this review. Thus, this study may help in further optimizing these thiazolidinone derivatives as more effective drug agents.

show abstract

Section: Biological Activities Of 4-thiazolidinonesmentioning

confidence: 99%

Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

Nirwan

Chahal

Kakkar

2019

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

show abstract

“…Stirring of 95 with 4-hydroxybenzaldehyde in hot DMF containing potassium carbonate afforded the respective ether 96 in 76% yield ( Scheme 25 ). 77 …”

Section: Synthesis Of Fused Heterocyclic Systemsmentioning

confidence: 99%

Recent advances in the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Previously, the same authors synthesized this class of molecules in PEG-400, but the reaction mixture was heated at 110 °C for 2 h, obtaining the desired compounds with modest final yields [ 38 ]. Instead, the DIL organocatalyst allowed to improve the reaction conditions (80 °C for 1 h) with excellent yields (81–92%).…”

Section: Applications In Organocatalysismentioning

confidence: 99%

Recent Advances in Imidazolium-Based Dicationic Ionic Liquids as Organocatalysts: A Mini-Review

et al. 2022

View full text Add to dashboard Cite

Imidazolium-based dicationic ionic liquids (DILs) are gaining considerable space in the field of organocatalysis mainly due to the opportunities in offering new possible applicable structural variations. In addition to the well-known variables which made the ionic liquids (ILs) famous as the type of cation and anion used, the nature of the molecular spacer moiety turns out a further possibility to improve some physicochemical properties, for example, solubility, acidity, electrochemical behavior, and so on. For this reason, this class of ionic liquids has been considered as possible competitors to their corresponding monocationic salts in replacing common catalysts in organic synthesis, particularly in cases in which their bidentate nature could positively affect the catalytic activity. This mini-review is intended to highlight the progress carried out in the last six years in the field of organocatalysis, including DILs as such and as hybrids with polymers, nanomaterials, and composites.

show abstract

New tetrazoloquinolinyl methoxyphenyl-4-thiazolidinones: synthesis and antihyperglycemic evaluation

Cited by 17 publications

References 63 publications

Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

Recent advances in the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs

Recent Advances in Imidazolium-Based Dicationic Ionic Liquids as Organocatalysts: A Mini-Review

Contact Info

Product

Resources

About