New Triterpenoids from the Stem Barks of Drypetes tessmanniana

Abstract

The MeOH extract of the stem barks of Drypetes tessmanniana (Euphorbiaceae) afforded two new triterpene derivatives characterized as 3b b-O-(E)-3,5-dihydroxycinnamoyl-11-oxo-olean-12-ene and 3b b,6a a-dihydroxylup-20(29)-ene together with seven known compounds. Their structures were established on the basis of spectral analysis.

Phytochemistry and pharmacology of the genus Drypetes: A review

“…chevalieri (Wansi et al, 2006(Wansi et al, , 2007, D. gerrardii (Ng´ang´a et al, 2008(Ng´ang´a et al, , 2012, D. parvifolia (Nenkep et al, 2008), D. tessmanniana (Dongfack et al, 2008), D. paxii (Chiozem et al, 2009), D.…”

“…tessmanniana (Dongfack et al, 2008) and D. gerrardii (Ng´ang´a et al, 2008, 2012Hata et al, 2014). Friedelane-3α,16β-diol (21), its isomer friedelane-3β,29β-diol (22) and the oxydized isomer 3-oxo-friedelan-29-ol (23) were reported from D. hieranensis and D. congestiflora Chuin & T.…”

“…The DCM-MeOH (1:1) extract of the stem of D. chevalieri afforded a triterpenoid named drypechevalin A or 11-oxo-β-amyrin-3β-ylcaffeate (60) (Wansi et al, 2006). From the MeOH extract of the stem bark of D. tessmanniana, a 3β-O-(E)-3,5-dihydroxycinnamoyl-11-oxo-olean-12-ene (61) was reported (Dongfack et al, 2008). From the DCM-MeOH (1:1) extract of the leaves of D. gerrardii, the saponin putranoside A (62) was isolated (Hata et al, 2014).…”

“…tessmanniana (Dongfack et al, 2008), and the EtOH extract of leaves and stems of D. hainanensis (Chen et al, 2014) (Fig. 6).…”

“…Stigmasterol (84), β-sitosterol (85) and their glycosylated (87) were isolated from the leaves of D. hieranensis (Chen et al, 1999), the stem bark of D. parvifolia (Nenkep et al, 2008), the stem bark of D. tessmanniana (Dongfack et al, 2008), the stems of D.…”