Newborn brain weight in relation to maturity, sex, and race

Abstract

Fresh brain weight, gestational age, body weight, sex, and race were collected from autopsy records of 782 newborns over a 10-year period. The brain weight of the mature newborn does not differ between males and females or between white and black infants. For the premature, however, brain weight is heavier in white males than in black males and in white females than in black females. These differences are similar to those found for adults in our previous studies, and they correspond to differences in gestational age and body weight in the subgroups. The differences in brain weight between races are best explained on the basis of environmental factors.

Brain mass estimation by head circumference and body mass methods in neonatal glycaemic modelling and control

“…Hence, there is an indication that any discrepancies in between the two methods of estimation are exacerbated in SGA infants. This result may be attributed to the median mass of 1055 g of the cohort from which Equation (2) was derived [25], versus the median mass of 750 g used here and 760 g in Le Compte et al [11].…”

“…Equation (2) is estimated using data from Ho et al [25]. This paper reports the mean and standard deviation body and brain mass for a range of preterm infants, divided into sub-cohorts by sex and ethnicity.…”

“…A model relating HC to brain mass from Cooke et al [22] is compared to the original NICING assumption that brain mass is 14% of , based on Ho et al [25] and in Equation (2).…”

Modeling the glucose regulatory system in extreme preterm infants

“…Glucose metabolism by the brain is relatively constant [47] and independent of insulin concentration [1]. The value used for CNS in this study was 8.8µmol/min/100g brain weight (0.088 mmol/min/kg brain weight) based on [48], where the average brain weight of the preterm infant at the age used in this cohort was estimated at 14% of body weight [49].…”

Age‐related changes of digital endocranial volume during human ontogeny: Results from an osteological reference collection

“…In fact, brain weight has sometimes been used as a diagnostic tool in the autopsy room (Marchand, 1902). Lesions, such as those caused by meningitis, hydrocephalus, gross malformation, hemorrhage, infarction, and necrosis, substantially affect brain weight in stillborn babies and infants (Ho et al, 1981).…”