NH2NH-MOF: a reaction matrix for the specific determination of small aldehydes by MALDI-MS

Zheng, Ruijuan; Xia, Yan

doi:10.1007/s00604-021-05143-y

Cited by 6 publications

(5 citation statements)

References 33 publications

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“…Table 3 summarizes the related components of typical COFs-MOFs composites and their applications reported in recent years. [170][171][172][173][181][182][183][184][185][186][187][188][189][190][191][192][193][194][195][196][197]…”

Section:  Cofs-mofs Compositesmentioning

confidence: 99%

“…TAPB + BETH ZPF-2 Biomacromolecule@COF-42-B Enzyme encapsulation [181] BTCA + TAPB UiO-66-NH 2 UiO-66-NH 2 @COF-TAPB-BTCA Adsorption [182] TMT + TFPT NH UiO@COF1 and UiO@COF2 Identification of PO 4 3and ATP [188] Tp + BD Tp-Cu-MOF Cu-MOF@TPBD Platelet-derived growth factor-BB (PDGF-BB) [189] Terephthalonitrile Co-MOF Co-MOF@TPN-COF Detection of ampicillin [190] TP + TTA NH 2 -MIL-88B(Fe) NMC Tp-TTA Anti-bacteria [191] TFPA + TAPA NH 2 -MIL-68 NH 2 -MIL-68@COF Detection of sulfonamides [192] Tp + Pa UiO-66-NH 2 UiO@TapbTp Anti-inflammatory drugs [193] Tp + Pa NH 2 -MIL-125(Ti) NH 2 -MIL-125(Ti)@TpPa-1 Detection of UO 2 2+ and Eu 3+ [194] PDA + BTCA Mn-MOF COF/Mn-MOF Lithium storage [195] BTCA + Pa MOF-UiO-66-NH 2 aza-MOF@COF Supercapacitor [196] DMTP + TAPB MOF of Bi-Mn-porphyrin (BM) MOF@COF Microwave thermal-dynamic therapy and anti-angiogenesis of colorectal cancer [197] Abbreviations: ATP, adenosine-5′-triphosphate; BETH, 2,5-bis(ethoxy)terephthalohydrazide; BTCA, 1,3,5-benzenetricarbaldehyde; DETH, 2,5-diethoxybenzene-1,4-dicarbohydrazide; FPBA, 4-formylphenylboronic acid; TAPA, tris(4-aminophenyl)amine; TFPA, tris(4-formylphenyl)amine; TFPT, 1,3,5-tris-(4-formyl-phenyl)triazine; TMT, 2,4,6-trimethyl-1,3,5triazine; TPA, terephthaldicarboxaldehyde; TPE, tetraamino-tetraphenylethylene.…”

Section: Precursors Of Cofsmentioning

confidence: 99%

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Composite materials based on covalent organic frameworks for multiple advanced applications

Chen

Wang

et al. 2023

Exploration

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Covalent organic frameworks (COFs) stand for a class of emerging crystalline porous organic materials, which are ingeniously constructed with organic units through strong covalent bonds. Their excellent design capabilities, and uniform and tunable pore structure make them potential materials for various applications. With the continuous development of synthesis technique and nanoscience, COFs have been successfully combined with a variety of functional materials to form COFs‐based composites with superior performance than individual components. This paper offers an overview of the development of different types of COFs‐based composites reported so far, with particular focus on the applications of COFs‐based composites. Moreover, the challenges and future development prospects of COFs‐based composites are presented. We anticipate that the review will provide some inspiration for the further development of COFs‐based composites.

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Section:  Cofs-mofs Compositesmentioning

confidence: 99%

Section: Precursors Of Cofsmentioning

confidence: 99%

Composite materials based on covalent organic frameworks for multiple advanced applications

Chen

Wang

et al. 2023

Exploration

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“…Thus far, nanomaterials, including titania particles, 23 silicon nanoparticles, 24 carbon-based materials, [25][26][27] and metal-organic frameworks, have been developed. 28 SALDI-MS has been widely used because of its low background interference in smallmolecule analysis. However, because the drying and crystallization processes cannot be precisely controlled, the material distribution on the target plate is often nonuniform, which will result in a random distribution of the substrate.…”

Section: -Hydroxycinnamic Acid [Chca]mentioning

confidence: 99%

“…The second is surface‐assisted laser desorption mass spectrometry (SALDI‐MS), 22 which is characterized by the use of nanomaterials as substrates instead of an organic matrix. Thus far, nanomaterials, including titania particles, 23 silicon nanoparticles, 24 carbon‐based materials, 25–27 and metal–organic frameworks, have been developed 28 . SALDI‐MS has been widely used because of its low background interference in small‐molecule analysis.…”

Section: Introductionmentioning

confidence: 99%

Covalent organic framework film–based laser desorption/ionization mass spectrometry for rapid and sensitive quantification of homocysteine in human serum

Chen

Ouyang

et al. 2023

Rapid Comm Mass Spectrometry

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Rationale Homocysteine (hcy) is a metabolite in the human body and an important determinant of cardiovascular health. To assist in the assessment of human cardiovascular safety, a rapid and accurate quantitative analysis method must be developed. Laser desorption/ionization mass spectrometry (LDI‐MS) has been widely used in biological, chemical, and medical analyses due to its excellent characteristics of high throughput, low sample consumption, and high speed. Here, an LDI‐MS method based on covalent organic framework (COF) film was developed for the rapid and sensitive determination of hcy in human serum using an isotope‐labeled internal standard. Methods We tried to cultivate COFs on indium−tin oxide substrate at room temperature to form a thin film, which was used in LDI‐MS. Compared with the traditional organic matrices, the COF film had a clean background and a high signal response for the detection of hcy. In addition, using COF film as the substrate, with a high signal intensity and a clean background, can be helpful to analyze a series of small molecules such as amino acids, bisphenols (Bps), estrogens, and drugs. We evaluated the limit of detection (LOD) and the reproducibility of this method. Finally, the calibration curve was constructed for the quantification of serum hcy using an isotope‐labeled internal standard and was applied for the rapid determination of hcy in clinical human serum. Results COF film–assisted LDI‐MS had a higher response signal and a cleaner background compared to four conventional organic matrices. The LOD of the method for hcy was 0.5 μmol/L, equivalent to 500 fmol. This method exhibited excellent performance for small‐molecule compounds, including amino acids, Bps, drugs, and estrogens. The reproducibilities of this method for shot‐to‐shot and dot‐to‐dot were determined to be good. This method was applied for the rapid analysis of hcy in clinical human serum, showing good correlation with those obtained by hospital testing. Conclusion The COF film–based LDI‐MS method had simple sample preparation, short analysis time, clean background, and good reproducibility for hcy analysis. As an important indicator of human health, the detection of serum hcy is of great significance to human health.

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“…Lots of small aldehydes are toxic, 1 and are a serious threat to ecological safety and human health, such as formaldehyde, [2][3][4] glyoxal, 5,6 acrolein, 7,8 benzaldehyde 9 and so on. Salicylaldehyde (SA) is one of the important derivatives of benzaldehyde and is often used in the production of coumarin, and the preparation of violet flavor, solvents, fragrances and intermediates of organic synthesis.…”

Section: Introductionmentioning

confidence: 99%

A highly stable and efficient benzothiadiazole-based fluorescence sensor for salicylaldehyde in aqueous solution

et al. 2023

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NH2NH-MOF: a reaction matrix for the specific determination of small aldehydes by MALDI-MS

Cited by 6 publications

References 33 publications

Composite materials based on covalent organic frameworks for multiple advanced applications

Composite materials based on covalent organic frameworks for multiple advanced applications

Covalent organic framework film–based laser desorption/ionization mass spectrometry for rapid and sensitive quantification of homocysteine in human serum

A highly stable and efficient benzothiadiazole-based fluorescence sensor for salicylaldehyde in aqueous solution

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