2022
DOI: 10.1039/d2tc01967a
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Ni@4H-chromene-based core–shell nanoparticles: highly sensitive and selective chemosensors for the radiosensitizer bromodeoxyuridine

Abstract: Regardless of the significant use of 5-bromo-2’-deoxyuridine (BrdU) as a radiosensitizer and diagnostic tool in cancer patients, some severe side effects and health issues like genetic mutations, birth defects, and...

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Cited by 6 publications
(3 citation statements)
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“…The obtained linear regression values can be written as an equation such as I p,a[μA]=−0.182[IUdR]/μM+69.568 with R 2 =0.9838, I p,c[μA] at −0.006 V=0.127[IUdR]/μM−28.295 with R 2 =0.9917, and I p,c[μA] at −0.72 V=0.1783[IUdR]/μM−47.948 with R 2 =0.9674. The limit of detection was found to be 13.8 nM calculated by 3‐sigma method [38] …”
Section: Resultsmentioning
confidence: 95%
See 1 more Smart Citation
“…The obtained linear regression values can be written as an equation such as I p,a[μA]=−0.182[IUdR]/μM+69.568 with R 2 =0.9838, I p,c[μA] at −0.006 V=0.127[IUdR]/μM−28.295 with R 2 =0.9917, and I p,c[μA] at −0.72 V=0.1783[IUdR]/μM−47.948 with R 2 =0.9674. The limit of detection was found to be 13.8 nM calculated by 3‐sigma method [38] …”
Section: Resultsmentioning
confidence: 95%
“…The limit of detection was found to be 13.8 nM calculated by 3sigma method. [38] LSV and DPV measurements were carried out for the further quantification of IUdR at Hg/KR-1@MWCNT/GCE in the presence of 0.1 M PBS. As displayed in Figure 6(D, E) the LSV and DPV response of Hg/KR-1@MWCNT/GCE to the sequential addition of IUdR concentration range varying from 0.025 μM-250 μM shows a decrease in anodic peak current intensity to each of the addition.…”
Section: Electrochemical Detection Of Iododeoxyuridine Using Hg/kr-1@...mentioning
confidence: 99%
“…Thus, organic nanoparticles (ONPs) were prepared owing to the poor solubility of receptor R1 in an aqueous medium. ONPs of receptor R1 were fabricated by the bottom-up approach of the reprecipitation technique. , For this purpose, first the receptor R1 solubility was analyzed in various organic solvents and subsequently DMSO solvent was chosen among all. 1 mM stock solution of receptor R1 was prepared in 5 mL of DMSO solvent, out of which 1 mL was injected dropwise in 100 mL of distilled water followed by ultrasonication for 30 min in order to get a stable dispersion of molecules in water (Figure S6A).…”
Section: Methodsmentioning
confidence: 99%