This paper aims to introduce a developed reading of Roederer's interpretation of pragmatic information as a good candidate for a Unifying Information Concept required for an as-yet-unavailable Science of Information. According to pragmatic information, information and information processing are exclusive attributes of biological systems related to the very definition of life. I will apply the notion to give new accounts in the following areas: (1) quantum interpretation: based on a modified version of David Bohm's interpretation of quantum mechanics, I propose an ontological, information-based interpretation of quantum mechanics which, unlike Roederer's interpretation, satisfies all conditions of pragmatic information; (2) artificial intelligence: the notion successfully distinguishes natural living systems from artifacts and natural non-living systems, providing a context to pose an information-based argument against the thesis of Strong Artificial Intelligence; (3) phenomenal consciousness: I will use pragmatic information to modify and update Chalmers's Double-aspect Theory of Information to be explanatorily more powerful regarding the physical aspect of his theory; (4) causation: based on pragmatic information, I pose a new account of causation which differentiates causation in biology from causation in natural abiotic world.