Niosomes as cutting edge nanocarrier for controlled and targeted delivery of essential oils and biomolecules

Purohit, Sejal; Tharmavaram, Maithri; Rawtani, Deepak; Prajapati, Prajesh; Pandya, H. G.; Dey, Aayush

doi:10.1016/j.jddst.2022.103438

Cited by 12 publications

(6 citation statements)

References 75 publications

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“…To remove obstinate pigmentation, the most recent lasers combine optical energy with intense pulsed light (IPL). This is an exciting development, as it makes it possible to treat patients more quickly and effectively than ever before [ 205 , 206 , 207 ].…”

Section: Modern Skin Pigmentation Treatments and Promising New Techno...mentioning

confidence: 99%

Skin Pigmentation Types, Causes and Treatment—A Review

Thawabteh,

Jibreen,

Karaman

et al. 2023

Molecules

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Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted by genetics, UV exposure, and some drugs. Patients’ physical appearance, psychological health, and social functioning are all impacted by a sizable number of skin conditions that cause pigmentary abnormalities. Hyperpigmentation, where pigment appears to overflow, and hypopigmentation, where pigment is reduced, are the two major classifications of skin pigmentation. Albinism, melasma, vitiligo, Addison’s disease, and post-inflammatory hyperpigmentation, which can be brought on by eczema, acne vulgaris, and drug interactions, are the most common skin pigmentation disorders in clinical practice. Anti-inflammatory medications, antioxidants, and medications that inhibit tyrosinase, which prevents the production of melanin, are all possible treatments for pigmentation problems. Skin pigmentation can be treated orally and topically with medications, herbal remedies, and cosmetic products, but a doctor should always be consulted before beginning any new medicine or treatment plan. This review article explores the numerous types of pigmentation problems, their causes, and treatments, as well as the 25 plants, 4 marine species, and 17 topical and oral medications now on the market that have been clinically tested to treat skin diseases.

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Section: Modern Skin Pigmentation Treatments and Promising New Techno...mentioning

confidence: 99%

Skin Pigmentation Types, Causes and Treatment—A Review

Thawabteh,

Jibreen,

Karaman

et al. 2023

Molecules

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Section: Eos In Niosomesmentioning

confidence: 99%

“…Niosomes exhibit physicochemical features akin to liposomes, yet they surpass them in terms of stability, simplicity of fabrication, and lower production expenses (Karim et al, 2010). Various EOs have been successfully incorporated into niosomes for different applications such as cosmetics, food packaging and pharmaceuticals (Purohit et al, 2022). In a recently published work, liposomal and niosomal nanoformulations of Achillea millefolium EO were synthesized and evaluated for their cytotoxicity against MCF‐7 cells.…”

Section: Nanoencapsulation Of Eos and Their Constituentsmentioning

confidence: 99%

Essential oils and their nanoformulations for breast cancer therapy

Thalappil,

Singh,

Carcereri de Prati

et al. 2023

Phytotherapy Research

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Breast Cancer (BC) is the most prevalent type of cancer in the world. Current treatments include surgery, radiation, and chemotherapy but often are associated with high toxicity to normal tissues, chemoresistance, and relapse. Thus, developing novel therapies which could combat these limitations is essential for effective treatment. In this context, phytochemicals are increasingly getting popular due to their safety profile, ability to efficiently target tumors, and circumvent limitations of existing treatments. Essential Oils (EOs) are mixtures of various phytochemicals which have shown potential anticancer activity in preclinical BC models. However, their clinical translation is limited by factors such as high volatility, low stability, and poor solubility. Nanotechnology has facilitated their encapsulation in a variety of nanostructures and proven to overcome these limitations. In this review, we have efficiently summarized the current knowledge on the anticancer effect of EOs and constituents in both in in vitro and in in vivo BC models. Further, we also provide a descriptive account on the potential of nanotechnology in enhancing the anti‐BC activity of EOs and their constituents. The papers discussed in this review were selected using the keywords “antiproliferative Essential Oils in breast cancer,” “anticancer activity of Essential Oil in breast cancer,” and “cytotoxicity of Essential Oils in breast cancer” performed in PubMed and ScienceDirect databases.

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“…The key to creating antibacterial food packaging material is incorporating antimicrobial agents, such as essential oils and their bioactive constituents, into polymeric materials 15 . Essential oils, natural antibacterial agents, are widely used in the medical, food, and cosmetic industries due to antioxidant, antibacterial, antiseptic, and antifungal properties 16–18 …”

Section: Introductionmentioning

confidence: 99%

“…15 Essential oils, natural antibacterial agents, are widely used in the medical, food, and cosmetic industries due to antioxidant, antibacterial, antiseptic, and antifungal properties. [16][17][18] Similar to most essential oil components, eugenol (Eu) possesses outstanding antimicrobial activity and has been applied in food preservation. [19][20][21] It has been categorized as generally recognized as safe by the Food and Drug Administration.…”

Section: Introductionmentioning

confidence: 99%