NIR-laser-triggered drug release from folate decorated albumin nanoparticles for synergistic chemo-photothermal tumor therapy

Li, Yanli; Wang, Tianyan; Liu, Yun; Xu, Yi; Sun, Zengxian; Yang, Guangsheng

doi:10.1016/j.jddst.2019.101156

Cited by 3 publications

(1 citation statement)

References 33 publications

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“…Unfortunately, the conventional anticancer drugs usually present poorly water-soluble, high toxicity, low accumulation in tumors, and poor bioavailability. [9][10][11] To address these problems, nanoscale drug delivery systems such as liposomes, [12][13][14][15] polymeric micelles, [16][17][18] protein-based nanoparticles [19][20][21] and dendrimers [22][23][24] have been used as drug carriers. Although they have been certified better therapeutic efficacy against tumors by improving the biodistribution and bioavailability of drugs, the carriers are largely limited by no therapeutic efficacy by themselves and low drug loading capacity.…”

Section: Introductionmentioning

confidence: 99%

Red‐Blood‐Cell‐Membrane‐Coated Metal‐Drug Nanoparticles for Enhanced Chemotherapy

Liang

Wang

2021

ChemBioChem

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To overcome high toxicity, low bioavailability and poor water solubility of chemotherapeutics, a variety of drug carriers have been designed. However, most carriers are severely limited by low drug loading capacity and adverse side effects. Here, a new type of metal-drug nanoparticles (MDNs) was designed and synthesized. The MDNs self-assembled with Fe(III) ions and drug molecules through coordination, resulting in nanoparticles with high drug loading. To assist systemic delivery and prolong circulation time, the obtained MDNs were camouflaged with red blood cell (RBCs) membranes

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