“…Cucurbitacin B (CuB), a member of the cucurbitacins, is extracted from Cucurbitaceae plants that have long been used in oriental medicines for their anti-inflammatory, antidiabetic and hepatoprotective effects [1,2,3]. Recently, accumulating evidence has demonstrated that CuB and its relatives inhibit the proliferation of many cancerous cells both in vitro and in xenografted tumor models, including breast cancer, glioblastoma multiforme, myeloid leukemia, pancreatic cancer, laryngeal cancer, hepatocellular carcinoma and melanoma cells [3,4,5,6,7,8,9,10].…”