Nitrogen-doped carbon nanodots prepared from polyethylenimine for fluorometric determination of salivary uric acid

Fabrication of nitrogen-enriched carbon dots with green fluorescence for enzyme-free detection of uric acid

“…Of note, the data show that the linear detection ranges and LOD are better than or comparable to those of the other methods (Table S2, ESI†). There are some reports on enzyme-free fluorescence detection of uric acid based on carbon dots, 42–44 for example, Yang et al developed an enzyme-free fluorescent sensor based on carbon dots and MnO 2 nanocomposites for indirectly monitoring uric acid in human urine samples. 42 Zhao et al realized the direct fluorescence detection of UA in urine based on carbon dots obtained by the hydrothermal treatment of pork.…”

Developing Activated Carbon Veil Electrode for Sensing Salivary Uric Acid

“…The peak current of UA increases linearly with an increase in its concentration in the range from 0.09 to 700 µM (Figure S5) and is described by Equation ( 6): I p (µA) = (0.36 ± 0.02) C (µM) + (0.076 ± 0.002), R 2 = 0.995 (6) The detection limit of the developed sensor was 0.05 µM, the limit of quantitative determination was 0.15 µM. The relative standard deviation of the analytical signal of 0.1 µM UA on one electrode was 4.2 % (n = 5), and for twenty different electrodes 7.4 %.…”

“…5 LOD-limit of detection. 6 LSV-linear sweep voltammetry; CA-chronoamperometry; DPV-differential-pulse voltammetry; CV-cyclic voltammetry; DP-ASV-differential pulse-anodic stripping voltammetry; A-amperometry; BIA-MPA-multiple-pulse amperometry combined with batch-injection analysis.…”

“…Biosensors 2021, 11, 287 2 of 14 A variety of methods can be used to measure UA in biological fluids, including fluorescent [6], chromatographic with mass spectrometry, electrochemical and fluorescence detection [1,7,8], enzymatic colorimetric [9], capillary electrophoresis with electrochemical detection [10,11], and electrochemical [12,13]. These methods have both benefits and limitations.…”

The analytical and biomedical applications of carbon dots and their future theranostic potential: A review

“…These properties arise from their inherent structural features such as low toxicity, biocompatibility and permeability, weak interactions with proteins, resistance to swelling and photobleaching, easy clearance from the body, low cost, and immune system evasion [4]. To exploit the unique properties of C-dots and their low cost and ease of synthesis, much work has been done in areas such as optical sensing [5,6], bioimaging [7], photocatalysis [8][9][10][11] and electrocatalysis [12][13][14]. Interestingly, imaging agents have played an essential role as a platform for real-time multimodal imaging-associated cancer therapy [15][16][17].…”