Nitroxide radical-modified CuS nanoparticles for CT/MRI imaging-guided NIR-II laser responsive photothermal cancer therapy

Abstract

Herein, we reported nitroxide radical-modified CuS nanoparticles (CuS–NO˙ NPs), and they exhibited a typical absorption peak at 1182 nm.

CuS nanoparticles anchored to g-C3N4 nanosheets for photothermal ablation of bacteria

“…Among these antimicrobial techniques, photothermal therapy (PTT) 17,18 -the combining of pulsed lasers with lightabsorbing materials possessing high light-thermal conversion efficiency under the near infrared (NIR) laser irradiation, has attracted much research attention. 19 In short, the photothermal materials could efficiently absorb the energy from NIR photons and convert it into thermal energy. The generated heat then exterminated the antibiotic-resistant bacteria and subsequently prevented the formation of biolm structures.…”

“…23 However, wide applications have been restricted by their inherent defects, such as poor biocompatibility, high cost, low photostability, tedious preparation procedures, and low targeting efficiency toward bacteria. Among these investigated materials, the copper suldes (CuS) 18,19,[24][25][26][27][28][29][30] stand out as suitable choices for photothermal therapy because of their excellent photothermal conversion efficiency in the NIR region and high intrinsic thermal conductivity. [31][32][33] However, the low surface area and easy sedimentation hindered their widely applications in PTT as a means of eliminating trapped bacteria.…”

Construction of Smart Nanotheranostic Platform Bi-Ag@PVP: Multimodal CT/PA Imaging-Guided PDT/PTT for Cancer Therapy

“…Ideal PTAs can efficiently convert light into heat; thus, good light energy conversion is a prerequisite of PTAs. 22 At present, indocyanine green (ICG) is the only PTA approved for clinical use. 23 However, the insufficient photothermal conversion efficiency and poor solubility limit its therapeutic effect on malignant tumors.…”

“…As another phototherapy strategy, PTT has attracted broad interest from researchers due to its high selectivity and minimal invasiveness, which requires photothermal agents (PTAs) to convert light energy into heat to kill tumor cells. Ideal PTAs can efficiently convert light into heat; thus, good light energy conversion is a prerequisite of PTAs . At present, indocyanine green (ICG) is the only PTA approved for clinical use .…”

Self-assembled CeVO4/Au heterojunction nanocrystals for photothermal/photoacoustic bimodal imaging-guided phototherapy

“…And the (PA) imaging provides a promising biomedical imaging modality, which provides higher spatial resolution and relatively deeper tissue penetration through the detection of ultrasonic signal waves. [35][36][37] Inorganic semiconductor nanomaterials have been widely used as photothermal agents, 38 photosensitizes 39 and multimode imaging agents [40][41][42] due to their unique optical performance. Cerium vanadate (CeVO 4 ), a kind of wide band gap inorganic semiconductor nanomaterials, 43 has relatively small optical cross-sections in the Vis/NIR regions.…”