“…It is worthy to mention that the association of human leukocyte antigens (HLA) with BP were studied more than three decades ago. 2-4 Smith et al, 2 found no association between HLA and idiopathic BP and stated that a lack of association does not exclude a correlation since the possibility exists that the disease is comprised of various etiologically different subgroups, some or all, being associated with different antigens. However, Schwartz et al, 3 found a possible association of BP with HLA-DR2, HLA-DR4, HLA-DRW6, and HLA-DRW7.…”