Nocardia Asteroides aortitis with perforation of the aorta

Allevato, Pat A.; Eisses, John F.; Mezger, Eugene; Fisher, Evelyn; Romig, Donald A.; Morales, Azorides R.

doi:10.1016/s0046-8177(85)80163-5

Cited by 26 publications

(13 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In four out of them 1,8,10,11 blood cultures were positive, but only three patients survived after treatment: two patients underwent aortic valve replacement 10,11 , while the third one 8 was cured only on antibiotic treatment, like our patient. In our patient it was not identified any other foci of nocardiosis and the infection occurred eight years after the surgery; he had two positive blood cultures to Nocardia spp.…”

supporting

confidence: 47%

See 1 more Smart Citation

Nocardial infections: report of 22 cases

Chedid

Porto³

et al. 2007

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

SUMMARYTwenty-two cases of nocardial infections were diagnosed in our city between 1977-1998. All patients whose clinical specimens showed Nocardia spp. at Gram stain, which were further confirmed by culture, were selected to be included in the study. Data from patients who were cured were compared with those from patients who died by statistical tests using EPIINFO version 6.04 software. Six isolates were identified as Nocardia asteroides complex, one as Nocardia asteroides sensu stricto and other as Nocardia brasiliensis. We had 17 cases of lung nocardiosis, being one out of them also a systemic disease. Other four cases of systemic nocardiosis were diagnosed: nocardial brain abscesses (one); nocardiosis of the jejunum (one); multiple cutaneous abscesses (one); and a case of infective nocardial endocarditis of prosthetic aortic valve. One patient had a mycetoma by N. brasiliensis. Fifteen (68.2%) out of 22 patients were immunosuppressed, being most (93.3%) by high-doses corticotherapy. Mortality by nocardial infection was 41%; mortality of systemic nocardiosis was 60%. Nocardiosis has a bad prognosis in immunosuppressed patients and also in non-immunosuppressed patients if the diagnosis is delayed. We propose that the delay in diagnosis should be examined in larger series to document its influence in the prognosis of the disease.

show abstract

supporting

confidence: 47%

“…Six reports of nocardial infective endocarditis of prosthetic valves were reported 1,8,[10][11][12]33 . In four out of them 1,8,10,11 blood cultures were positive, but only three patients survived after treatment: two patients underwent aortic valve replacement 10,11 , while the third one 8 was cured only on antibiotic treatment, like our patient.…”

mentioning

confidence: 99%

Nocardial infections: report of 22 cases

Chedid

Porto³

et al. 2007

Rev. Inst. Med. trop. S. Paulo

View full text Add to dashboard Cite

show abstract

“…The brain is the most frequent nonpulmonary site involved in disseminated nocardiosis (167,176,270,427,580), and cerebral nocardiosis is an important cause of cerebral spaceoccupying lesions. However, the infection may also involve many other deep organs, including the kidneys (9,307,466,497,654), spleen (307,654), liver (307,460,484,497,654) and, rarely, bone (10,20,26,139,232,325,327,377,446,487,525,652), skin (71,127,282,416,658), and joints (71,111,123,144,299). In the brain and other organs, abscess formation is a particularly common pathologic manifestation of disseminated nocardiosis (457,657).…”

Section: Epidemiologic Aspects Of Infection In Humansmentioning

confidence: 99%

The medically important aerobic actinomycetes: epidemiology and microbiology

1994

View full text Add to dashboard Cite

The aerobic actinomycetes are soil-inhabiting microorganisms that occur worldwide. In 1888, Nocard first recognized the pathogenic potential of this group of microorganisms. Since then, several aerobic actinomycetes have been a major source of interest for the commercial drug industry and have proved to be extremely useful microorganisms for producing novel antimicrobial agents. They have also been well known as potential veterinary pathogens affecting many different animal species. The medically important aerobic actinomycetes may cause significant morbidity and mortality, in particular in highly susceptible severely immunocompromised patients, including transplant recipients and patients infected with human immunodeficiency virus. However, the diagnosis of these infections may be difficult, and effective antimicrobial therapy may be complicated by antimicrobial resistance. The taxonomy of these microorganisms has been problematic. In recent revisions of their classification, new pathogenic species have been recognized. The development of additional and more reliable diagnostic tests and of a standardized method for antimicrobial susceptibility testing and the application of molecular techniques for the diagnosis and subtyping of these microorganisms are needed to better diagnose and treat infected patients and to identify effective control measures for these unusual pathogens. We review the epidemiology and microbiology of the major medically important aerobic actinomycetes.

show abstract

“…Three cases of Nocardia aortitis at the aortotomy site after aortic valve replacement have been documented. 6,7 There is one reported case of abdominal aortic aneurysm secondarily infected by Nocardia 8 and one case of middle cerebral artery aneurysm in a young patient with central nervous system Nocardia abscesses. 9 Nocardia was first described by French veterinarian Edmond Nocard in cows on the island of Guadeloupe in 1888.…”

Section: Discussionmentioning

confidence: 99%

Nocardia asteroides–Infected Aneurysm of the Aorta: Case Report and Review of the Literature

2006

View full text Add to dashboard Cite

Infected aneurysms of the aorta were first described as a result of septic emboli or contiguous spread from bacterial endocarditis and are usually caused by Staphylococcus or Salmonella species. We report a case of Nocardia-associated infected aneurysm of the native suprarenal aorta in an immunocompromised host. Surgical management consisted of placement of an interposition cryopreserved aortic homograft. Nocardia asteroides was identified on a microbiology specimen of the aorta and both microbiology and pathology specimens of the splenic tissue. To the best of our knowledge, this represents the first carefully documented, unique case of a Nocardia-infected aneurysm treated with homograft interposition. In addition, pathologic and microbiologic data are included from the postmortem examination 10 months later.

show abstract

Nocardia Asteroides aortitis with perforation of the aorta

Cited by 26 publications

References 20 publications

Nocardial infections: report of 22 cases

Nocardial infections: report of 22 cases

The medically important aerobic actinomycetes: epidemiology and microbiology

Nocardia asteroides–Infected Aneurysm of the Aorta: Case Report and Review of the Literature

Contact Info

Product

Resources

About