An account of thelotremoid species ofGraphidaceaein India is provided, which includes 124 species in 24 genera.OcellulariaandThelotremaare the most diverse genera represented by 34 and 18 species, respectively. Type specimens were re-examined and additional samples studied morphologically and chemically. One new species,Ocellularia upretiiS. Joshi, Divakar, Lumbsch & Lücking, is described; it is characterized by a greyish green thallus, porinoid ascomata, brown proper exciple, simple, carbonized columella, clear hymenium, transversely septate, amyloid ascospores of 110–125×15–20 µm and an absence of secondary metabolites.Asteristion australianum,Astrochapsa mirabilis,Cruentotrema cruentatum,C. kurandense,Ocellularia violaceaandThelotrema adjectumare reported as new to the country, andAstrochapsa mirabilis,Melanotrema submicrosporoides,Ocellularia annuloelevata,O. subkeralensisandRhabdodiscus verrucoisidiatusare proposed as new combinations.Diploschistes awasthii,Ocellularia gupeti,O. leucina, O. mahabalei,Thelotrema confertumandT. verrucorugosumare synonymized underD. scruposus,O. neomasonhalei,O. urceolaris,O. thelotremoides,Chapsa leprocarpoidesandT. rugatulum, respectively, withOcellularia canarianaandO. verrucomarginatareduced to synonymy withO. allosporoides.