Non-celiac gluten intolerance in patients with scleroderma.

Nisihara, Renato; Koubik, Mariana Aguiar; Mateus, M.A.; Kotze, Lorete da Silva; Skare, Thelma Larocca

doi:10.1016/j.jbspin.2018.01.017

Cited by 1 publication

(1 citation statement)

References 8 publications

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“…No studies assessed CD in children affected with systemic scleroderma (sSC). However, Nisihara et al tested 60 adult patients affected with sSC for EmA and AGA IgA/IgG: all samples turned out negative [61]. Similarly, Forbess et al screened 72 adult SSc patients by testing tTG IgA/IgG and DGP IgA/IgG: three patients tested positive for any markers, but no one was confirmed as being affected with CD [62].…”

Section: Celiac Disease In Other Pediatric Rheumatic Disordersmentioning

confidence: 99%

Celiac Disease in Juvenile Idiopathic Arthritis and Other Pediatric Rheumatic Disorders

Poddighe

Romano

Dossybayeva

et al. 2022

JCM

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Celiac Disease (CD) is an immune-mediated and gluten-related disorder whose prevalence is higher in children affected with other autoimmune disorders, including diabetes mellitus type 1, autoimmune thyroiditis, and others. As regards Juvenile Idiopathic Arthritis (JIA) and other pediatric rheumatic disorders, there is no clear recommendation for CD serological screening. In this review, we analyze all the available clinical studies investigating CD among children with JIA (and other rheumatic diseases), in order to provide objective data to better understand the necessity of CD serological screening during the follow-up. Based on the present literature review and analysis, >2.5% patients with JIA were diagnosed with CD; however, the CD prevalence in JIA patients may be even higher (>3–3.5%) due to several study limitations that could have underestimated CD diagnosis to a variable extent. Therefore, serological screening for CD in children affected with JIA could be recommended due to the increased CD prevalence in these patients (compared to the general pediatric population), and because these JIA patients diagnosed with CD were mostly asymptomatic. However, further research is needed to establish a cost-effective approach in terms of CD screening frequency and modalities during the follow-up for JIA patients. Conversely, at the moment, there is no evidence supporting a periodical CD screening in children affected with other rheumatic diseases (including pediatric systemic lupus erythematosus, juvenile dermatomyositis, and systemic sclerosis).

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Section: Celiac Disease In Other Pediatric Rheumatic Disordersmentioning

confidence: 99%