Non-diarrhoeic pigs as source of highly virulent and multidrug-resistant non-typhoidal Salmonella

Karabasanavar, Nagappa S.; Sivaraman, G.K.; Satheesha, S. P.; Nair, Archana S.; Vijayan, Ardhra; Rajan, Vineeth; Girish, P. S.

doi:10.1007/s42770-022-00700-w

Cited by 8 publications

(3 citation statements)

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“…In the current study, Derby was the most prevalent S. enterica serotype (abbreviated as S. Derby), matching previous results from other regions and nations [29,30]. S. Derby is one of the top ten serotypes isolated from human salmonellosis infections in many countries, including Taiwan [14,[30][31][32]. In addition, a large S. Derby clone spread from pigs to humans in Europe [33,34].…”

Section: Discussionsupporting

confidence: 88%

Prevalence, Serotypes, and Antimicrobial Resistance Patterns of Non-Typhoid Salmonella in Food in Northern Taiwan

et al. 2022

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Salmonella is one of the most common bacteria causing food poisoning worldwide. We evaluated the prevalence, the serotypes, and the antimicrobial resistance (AMR) of Salmonella isolates from many kinds of food, particularly pork and chicken in retail, in Taiwan between January 2017 and December 2019. The E-test was used to assess antimicrobial susceptibility and a polymerase chain reaction was performed for serotyping. A total of 459 different foods were investigated, and 117 Salmonella strains were isolated. Retail pork and chicken were the most common Salmonella-contaminated foods (64.1% and 29.1%, respectively). Of the 117 isolates, 23 serotypes were identified. The serotypes Derby (16.2%), Anatum (13.7%), and Agona (8.5%) were the most prevalent. The resistance rates to ciprofloxacin, ceftriaxone, and carbapenem were 41.9%, 11.1%, and 1.7%, respectively. The Derby and Anatum serotypes were prevalent in chicken and pork; the Anatum serotype had significantly higher ciprofloxacin and ceftriaxone resistance rates and was highly prevalent in 2017 and 2018. Multi-locus sequence typing analysis revealed that the 58 randomly chosen Salmonella isolates belonged to 18 sequence types (STs). ST64 (Anatum, 16 out of 58, 27.6%) was the most common, followed by ST321 (Muenster, 6/58, 10.3%), ST831 (Give, 5/58, 8.6%), ST155 (London, 4/58, 6.9%) and ST314 (Kentucky, 4/58, 6.9%). Multidrug-resistant Salmonella strains were remarkably observed in the serotypes Anatum (ST64) and Goldcoast (ST358). This study revealed that retail pork was commonly contaminated with antimicrobial-resistant Salmonella. Thus, periodic investigations of Salmonella serotypes and AMR are needed.

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Section: Discussionsupporting

confidence: 88%

Prevalence, Serotypes, and Antimicrobial Resistance Patterns of Non-Typhoid Salmonella in Food in Northern Taiwan

et al. 2022

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“…Tetracycline resistance genes ( tetA ) and sulfonamide-trimethoprim ( sul1 and dfrA1 ) were also detected in high frequency. These genes were also common in other studies from the region (Lapierre et al, 2008; Thai et al, 2012; Prasertsee et al, 2019; Karabasanavar et al, 2022), reflected in the high rates of resistance to β-lactam, tetracycline, and sulfonamide-trimethoprim.…”

Section: Discussionmentioning

confidence: 64%

Colistin resistance and resistance determinants are mobile amongSalmonella entericaisolates from diseased and healthy pigs in Thailand

Prasertsee

Pascoe

Patchanee

2023

Preprint

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Salmonella is an important enteric pathogen that poses a threat to human and livestock animal health, with emerging multidrug resistance (MDR) a major public health issue globally. We investigated the prevalence of Salmonella in healthy and diseased pigs from Thai pig farms and determined their phenotypic and genotypic antimicrobial resistance profiles. A total of 150 fecal samples were collected from pigs housed in pens from four separate pig farms in southern Thailand and tested for the presence of Salmonella. Confirmed Salmonella isolates were tested for their susceptibility to 11 antimicrobials, and PCR used to detect known antimicrobial resistance genes (ARGs). Salmonella isolates were cultured from 69% (103/150) of all fecal samples, with higher prevalence in disease pigs (12/15; 80%), compared with healthy pigs (91/135; 67%). Serotype Rissen was the most frequently identified serotype among the Salmonella isolates. Resistance to ampicillin (AMP) (97%), sulfonamide-trimethoprim (SXT) (97%), and tetracycline (TET) (94%) were the most common phenotypes observed. The most common ARGs identified were blaTEM gene (99.%), tetA (87%), sul1 (77%), and dfrA1 (74%), and more than 95% of the Salmonella isolates tested were MDR - based on resistance to three or more antimicrobial classes. The most common antimicrobial resistance pattern exhibited was AMP-TET-SXT (76%), and resistance to colistin (via the mcr-1 gene) was observed in both healthy and diseased pigs. The clonal groups of PFGE analysis in serotype Typhimurium revealed the genetic relationship among Salmonella isolated from healthy and diseased pigs from different pig farms.

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“…In addition, S . Weltevreden has been detected or isolated from animal, food, and environmental samples ( 29 – 31 ). Therefore, continuously monitoring the distribution and genomic characteristics of S .…”

Section: Introductionmentioning

confidence: 99%

Genomic Characterization of Salmonella enterica serovar Weltevreden Associated with Human Diarrhea

et al. 2023

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Non-diarrhoeic pigs as source of highly virulent and multidrug-resistant non-typhoidal Salmonella

Cited by 8 publications

References 50 publications

Prevalence, Serotypes, and Antimicrobial Resistance Patterns of Non-Typhoid Salmonella in Food in Northern Taiwan

Prevalence, Serotypes, and Antimicrobial Resistance Patterns of Non-Typhoid Salmonella in Food in Northern Taiwan

Colistin resistance and resistance determinants are mobile amongSalmonella entericaisolates from diseased and healthy pigs in Thailand

Genomic Characterization of Salmonella enterica serovar Weltevreden Associated with Human Diarrhea

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