Non-gadolinium dynamic angiography of the neurovasculature using arterial spin labeling MRI: preliminary experience in children

Hu, Houchun H.; Pokorney, Amber; Stefani, Niccolo; Chia, Jonathan M.; Miller, Jeffrey H

doi:10.1007/s10334-016-0589-5

Cited by 6 publications

(7 citation statements)

References 12 publications

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“…109 Both PASL and PCASL can be used for ASL-MRA. PASL with a Look-Locker readout has already proved its clinical usefulness in several studies 101,104,110,111 and is particularly good at visualizing the early inflow phase of the proximal arteries. However, vessel-selective PASL has some difficulties (see below), which makes PCASL a preferred option for vessel-selective MRA.…”

Section: Asl Angiography (Asl-mra)mentioning

confidence: 99%

Recent Technical Developments in ASL: A Review of the State of the Art

Hernandez‐García

Aramendía‐Vidaurreta

Bolar³

et al. 2022

Magnetic Resonance in Med

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This review article provides an overview of a range of recent technical developments in advanced arterial spin labeling (ASL) methods that have been developed or adopted by the community since the publication of a previous ASL consensus paper by Alsop et al. It is part of a series of review/recommendation papers from the International Society for Magnetic Resonance in Medicine Perfusion Study Group. Here, we focus on advancements in readouts and trajectories, image reconstruction, noise reduction, partial volume correction, quantification of nonperfusion parameters, fMRI, fingerprinting, vessel selective ASL, angiography, deep learning, and ultrahigh field ASL. We aim to provide a high level of understanding of these new approaches and some guidance for their implementation, with the goal of facilitating the adoption of such advances by research groups and by MRI vendors. Topics outside the scope of this article that are reviewed at length in separate articles include velocity selective ASL, multiple‐timepoint ASL, body ASL, and clinical ASL recommendations.

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Section: Asl Angiography (Asl-mra)mentioning

confidence: 99%

Recent Technical Developments in ASL: A Review of the State of the Art

Hernandez‐García

Aramendía‐Vidaurreta

Bolar³

et al. 2022

Magnetic Resonance in Med

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“…As an advanced ASL technique, contrast inherent inflow-enhanced multiphase angiography (CINEMA), introduced by Nakamura et al, provides the information on hemodynamics and structure of vessels in the target tissue without contrast agents [ 66 , 67 ]. The CINEMA technique requires PASL or pCASL tagging scheme and provides multi-timepoint data by varying the delay time interval between labeling and imaging at the slices of interest [ 68 , 69 ]. Iryo et al reported excellent agreement between CINEMA and digital subtraction angiography in visualizing the site of dural arteriovenous fistulas, including the fistula, the feeding arteries, and the draining veins [ 70 ].…”

Section: Clinical Applications Of 3d Tse Pcasl In the Head And Neckmentioning

confidence: 99%

“…Iryo et al reported excellent agreement between CINEMA and digital subtraction angiography in visualizing the site of dural arteriovenous fistulas, including the fistula, the feeding arteries, and the draining veins [ 70 ]. Hu et al successfully documented the intracranial AVM case that showed the nidus and the feeder arteries on CINEMA [ 68 ]. This technique can be applied to head and neck AVM, as shown in Figure 6 .…”

Section: Clinical Applications Of 3d Tse Pcasl In the Head And Neckmentioning

confidence: 99%

Pseudocontinuous Arterial Spin Labeling: Clinical Applications and Usefulness in Head and Neck Entities

Tanaka

Umino

Maeda

et al. 2022

Cancers

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As functional magnetic resonance imaging, arterial spin labeling (ASL) techniques have been developed to provide quantitative tissue blood flow measurements, which can improve the performance of lesion diagnosis. ASL does not require contrast agents, thus, it can be applied to a variety of patients regardless of renal impairments and contrast agent allergic reactions. The clinical implementation of head and neck lesions is limited, although, in recent years, ASL has been increasingly utilized in brain lesions. Here, we review the development of the ASL techniques, including pseudocontinuous ASL (pCASL). We compare readout methods between three-dimensional (3D) turbo spin-echo and 2D echo planar pCASL for the clinical applications of pCASL to head and neck lesions. We demonstrate the clinical usefulness of 3D pCASL for diagnosing various entities, including inflammatory lesions, hypervascular lesions, and neoplasms; for evaluating squamous cell carcinoma (SCC) treatment responses, and for predicting SCC prognosis.

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“…31 However, none of these three options should be considered to provide a perfect solution, which explains why PASL is still considered as one of preferred labeling techniques for dynamic ASL-MRA, and has proved its clinical usefulness in several previous clinical studies. [2][3][4][5] When imaging static 3D-MRA, however, the abovementioned dilemma is no longer relevant, and long pCASL labeling duration will ensures visualization of the complete arterial trees from proximal to distal vessels with adequate SNR. 16,25,27 Moreover, a hybrid of pCASL and PASL was suggested when using large FOV for imaging of extracranial carotid arteries, which could also minimize disappearance of the arterial signal due to fresh unlabeled blood flowing into the imaging volume.…”

Section: Labeling Module (General)mentioning

confidence: 99%

“…By taking advantage of this completely non-invasive feature, many studies were conducted to demonstrate that ASL can be an alternative technique for other more invasive techniques using X-ray and/or contrast agent. [1][2][3][4][5][6][7] This would especially be important for pediatric patients who need repetitive examinations to monitor disease progression. Whereas MR contrast agents used to be considered relatively safe, due to the established link between several linear gadolinium contrast agents and nephrogenic systemic fibrosis in patients with poor renal function as well as the recent observation of gadolinium deposition in the brain, 8 the European Medicines Agency decided to recommend the suspension of the use of four linear MR contrast agents and advise to limit the use of gadolinium based contrast agents to the lowest dose for diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Intracranial 3D and 4D MR Angiography Using Arterial Spin Labeling: Technical Considerations

Suzuki

Fujima

Osch

2020

MRMS

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In the 1980's some of the earliest studies of arterial spin labeling (ASL) MRI have demonstrated its ability to generate MR angiography (MRA) images. Thanks to many technical improvements, ASL has been successfully moving its position from the realm of research into the clinical area, albeit more known as perfusion imaging than as MRA. For MRA imaging, other techniques such as time-of-flight, phase contrast MRA and contrast-enhanced (CE) MRA are more popular choices for clinical applications. In the last decade, however, ASL-MRA has been experiencing a remarkable revival, especially because of its non-invasive nature, i.e. the fact that it does not rely on the use of contrast agent. Very importantly, there are additional benefits of using ASL for MRA. For example, its higher flexibility to achieve both high spatial and temporal resolution than CE dynamic MRA, and the capability of vessel specific visualization, in which the vascular tree arising from a selected artery can be exclusively visualized. In this article, the implementation and recent developments of ASL-based MRA are discussed; not only focusing on the basic sequences based upon pulsed ASL or pseudo-continuous ASL, but also including more recent labeling approaches, such as vessel-selective labeling, velocity-selective ASL, vessel-encoded ASL and time-encoded ASL. Although these ASL techniques have been already utilized in perfusion imaging and their usefulness has been suggested by many studies, some additional considerations should be made when employing them for MRA, since there is something more than the difference of the spatial resolution of the readout sequence. Moreover, extensive discussion is included on what readout sequence to use, especially by highlighting how to achieve high spatial resolution while keeping scan-time reasonable such that the ASL-MRA sequence can easily be included into a clinical examination.

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Non-gadolinium dynamic angiography of the neurovasculature using arterial spin labeling MRI: preliminary experience in children

Abstract: There is a steadily rising concern in adults and children over the potential effects of intracranial deposition of gadolinium. CINEMA is therefore a viable alternative in dynamic neurovascular imaging.

Cited by 6 publications

References 12 publications

Recent Technical Developments in ASL: A Review of the State of the Art

Recent Technical Developments in ASL: A Review of the State of the Art

Pseudocontinuous Arterial Spin Labeling: Clinical Applications and Usefulness in Head and Neck Entities

Intracranial 3D and 4D MR Angiography Using Arterial Spin Labeling: Technical Considerations

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