Non-intrusive approaches for the construction of computational vademecums face different challenges, especially when a parameter variation affects the physics of the problem considerably. In these situations, classical interpolation becomes inaccurate. Therefore, classical approaches for the construction of an offline computational vademecum, typically by using model reduction techniques, are no longer valid. Such problems are faced in different physical simulations, for example welding path problems, resin transfer molding, or sheet compression molding, among others. In such situations, the interpolation of precomputed solutions at prescribed parameter values (built using either intrusive or non intrusive techniques) generates spurious numerical artifacts. In this work, we propose an alternative interpolation and simulation strategy by using physically-based morphing of spaces. The morphing will transform the uncompatibe physical domains of the problem's solution into a compatible one, where an interpolation free of artifacts can be performed. Later on, an inverse transformation can be used to push-back the solution. Different relevant examples are illustrated in this work to motivate the use of the proposed method.