Non-invasive dynamic assessment of the elasticity of intracranial structures

Pranevicius, Osvaldas; Bertašius, Kęstutis; Pranevicius, Mindaugas; Jaržemskas, Egidijus

doi:10.1111/j.1600-0404.1992.tb05134.x

Cited by 13 publications

(3 citation statements)

References 8 publications

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“…Freeze-substitution electron microscopic studies of hy-3 mutant mice show that the extracellular compartment in the superficial cerebral cortex is initially compressed and subsequently enlarged [ 9 ]. Increased electrical impedance has been interpreted as a reflection of decreased water content in thalamus of hydrocephalic cats [ 10 ]; similar findings have been obtained in human studies [ 11 , 12 ]. Apparent diffusion coefficient (ADC) mapping in rats with hydrocephalus suggest that the movement of water in rat brain is restricted in gray matter but not in white matter [ 13 ].…”

Section: Introductionsupporting

confidence: 58%

Effect of hydrocephalus on rat brain extracellular compartment

Bigio

Enno

2008

Fluids Barriers CNS

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Section: Introductionsupporting

confidence: 58%

Effect of hydrocephalus on rat brain extracellular compartment

Bigio

Enno

2008

Fluids Barriers CNS

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“…The concept of an increasing ICP correlating with changes in transcranial propagation of ultrasonic impulses was described in the late 1980s [ 63 , 64 ] and in 1992 [ 65 , 66 ]. In multiple studies (1994–2001), waveform analysis of TCD blood flow velocity in the middle cerebral arteries revealed a high potential for the monitoring of the CPP [ 67 , 68 , 69 , 70 ].…”

Section: Approaches Of Non-invasive Measurementsmentioning

confidence: 99%

Non-Invasive Intracranial Pressure Monitoring

Müller

Henkes

Gounis³

et al. 2023

JCM

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(1) Background: Intracranial pressure (ICP) monitoring plays a key role in the treatment of patients in intensive care units, as well as during long-term surgeries and interventions. The gold standard is invasive measurement and monitoring via ventricular drainage or a parenchymal probe. In recent decades, numerous methods for non-invasive measurement have been evaluated but none have become established in routine clinical practice. The aim of this study was to reflect on the current state of research and shed light on relevant techniques for future clinical application. (2) Methods: We performed a PubMed search for “non-invasive AND ICP AND (measurement OR monitoring)” and identified 306 results. On the basis of these search results, we conducted an in-depth source analysis to identify additional methods. Studies were analyzed for design, patient type (e.g., infants, adults, and shunt patients), statistical evaluation (correlation, accuracy, and reliability), number of included measurements, and statistical assessment of accuracy and reliability. (3) Results: MRI-ICP and two-depth Doppler showed the most potential (and were the most complex methods). Tympanic membrane temperature, diffuse correlation spectroscopy, natural resonance frequency, and retinal vein approaches were also promising. (4) Conclusions: To date, no convincing evidence supports the use of a particular method for non-invasive intracranial pressure measurement. However, many new approaches are under development.

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“…Lateralized asymmetries in TCD pulsatility correlate with lesion volume in intracerebral hemorrhage, and are believed to reflect compartmentalized ICP gradients [25]. Promising new applications using ultrasound technology to estimate ICP noninvasively have been described, but have not yet been validated in the clinical setting [26–28].…”

Section: Icp Monitoringmentioning

confidence: 99%

Critical Care Management of Increased Intracranial Pressure

Mayer

Chong

2002

J Intensive Care Med

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Increased intracranial pressure (ICP) is a pathologic state common to a variety of serious neurologic conditions, all of which are characterized by the addition of volume to the intracranial vault. Hence all ICP therapies are directed toward reducing intracranial volume. Elevated ICP can lead to brain damage or death by two principle mechanisms: (1) global hypoxic‐ischemic injury, which results from reduction of cerebral perfusion pressure (CPP) and cerebral blood flow, and (2) mechanical compression, displacement, and herniation of brain tissue, which results from mass effect associated with compartmentalized ICP gradients. In unmonitored patients with acute neurologic deterioration, head elevation (30 degrees), hyperventilation (pCO2 26–30 mmHg), and mannitol (1.0–1.5 g/kg) can lower ICP within minutes. Fluid‐coupled ventricular catheters and intraparenchymal pressure transducers are the most accurate and reliable devices for measuring ICP in the intensive care unit (ICU) setting. In a monitored patient, treatment of critical ICP elevation (>20 mmHg) should proceed in the following steps: (1) consideration of repeat computed tomography (CT) scanning or consideration of definitive neurosurgical intervention, (2) intravenous sedation to attain a quiet, motionless state, (3) optimization of CPP to levels between 70 and 110 mmHg, (4) osmotherapy with mannitol or hypertonic saline, (5) hyperventilation (pCO2 26–30 mmHg), (6) high‐dose pentobarbital therapy, and (7) systemic cooling to attain moderate hypothermia (32–33°C). Placement of an ICP monitor and use of a stepwise treatment algorithm are both essential for managing ICP effectively in the ICU setting.

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Non-invasive dynamic assessment of the elasticity of intracranial structures

Cited by 13 publications

References 8 publications

Effect of hydrocephalus on rat brain extracellular compartment

Effect of hydrocephalus on rat brain extracellular compartment

Non-Invasive Intracranial Pressure Monitoring

Critical Care Management of Increased Intracranial Pressure

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