Non-invasive wearable electrochemical sensors: a review

Bandodkar, Amay J.; Wang, Joseph

doi:10.1016/j.tibtech.2014.04.005

Cited by 1,040 publications

(761 citation statements)

References 66 publications

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“…These wearable sensors, which can be concealed in almost any artistic tattoo pattern, can offer substantial insight into the wearer's health 317, 318. The majority of the developed tattoo‐based diagnostic devices have so far been based on body sweat due to the wide range of information that it can provide on patient health.…”

Section: Healthcare Monitors For Empowering the Patientmentioning

confidence: 99%

Blending Electronics with the Human Body: A Pathway toward a Cybernetic Future

et al. 2018

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At the crossroads of chemistry, electronics, mechanical engineering, polymer science, biology, tissue engineering, computer science, and materials science, electrical devices are currently being engineered that blend directly within organs and tissues. These sophisticated devices are mediators, recorders, and stimulators of electricity with the capacity to monitor important electrophysiological events, replace disabled body parts, or even stimulate tissues to overcome their current limitations. They are therefore capable of leading humanity forward into the age of cyborgs, a time in which human biology can be hacked at will to yield beings with abilities beyond their natural capabilities. The resulting advances have been made possible by the emergence of conformal and soft electronic materials that can readily integrate with the curvilinear, dynamic, delicate, and flexible human body. This article discusses the recent rapid pace of development in the field of cybernetics with special emphasis on the important role that flexible and electrically active materials have played therein.

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Section: Healthcare Monitors For Empowering the Patientmentioning

confidence: 99%

Blending Electronics with the Human Body: A Pathway toward a Cybernetic Future

et al. 2018

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“…Recent advances (108)(109)(110)(111)(112)(113)(114)(115) in integrating electronics onto low-elastic modulus polymer substrates and other moldable materials that are conformal, biocompatible, and, in some instances, even self-powered (116) are opening up a large menu of wearable devices based on mechanical, electronic, or electrochemical signal transduction (117,118). A large fraction of these devices contain some nanotechnology, with a scientific basis that can be traced back to early demonstrations of nanotube (119) or nanowire (120,121) sensors and the integration of nanowires and nanotubes onto plastic substrates (122,123).…”

Section: Nanomechanical and Nanoelectronic Devices And Wellness Monitmentioning

confidence: 99%

Nanotechnologies for biomedical science and translational medicine

Heath

2015

Proc. Natl. Acad. Sci. U.S.A.

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In 2000 the United States launched the National Nanotechnology Initiative and, along with it, a well-defined set of goals for nanomedicine. This Perspective looks back at the progress made toward those goals, within the context of the changing landscape in biomedicine that has occurred over the past 15 years, and considers advances that are likely to occur during the next decade. In particular, nanotechnologies for health-related genomics and single-cell biology, inorganic and organic nanoparticles for biomedicine, and wearable nanotechnologies for wellness monitoring are briefly covered.nanotechnology | biotechnology | nanomedicine

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“…Significant recent efforts have thus been made toward the development of soft, epidermally mounted systems 1, 2, 3. At the same time, wearable devices should monitor interesting and/or actionable parameters, and thus, significant research activity has augmented the measurement of vital signs and motion with the monitoring of biochemical markers 4, 5, 6, 7, 8. Recent efforts have focused on epidermal biomonitoring systems of two readily obtainable biofluids: skin interstitial fluid (ISF)9, 10, 11, 12 and sweat 13, 14, 15, 16, 17, 18, 19.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Monitoring of Sweat and Interstitial Fluid Using a Single Wearable Biosensor Platform

et al. 2018

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The development of wearable biosensors for continuous noninvasive monitoring of target biomarkers is limited to assays of a single sampled biofluid. An example of simultaneous noninvasive sampling and analysis of two different biofluids using a single wearable epidermal platform is demonstrated here. The concept is successfully realized through sweat stimulation (via transdermal pilocarpine delivery) at an anode, alongside extraction of interstitial fluid (ISF) at a cathode. The system thus allows on‐demand, controlled sampling of the two epidermal biofluids at the same time, at two physically separate locations (on the same flexible platform) containing different electrochemical biosensors for monitoring the corresponding biomarkers. Such a dual biofluid sampling and analysis concept is implemented using a cost‐effective screen‐printing technique with body‐compliant temporary tattoo materials and conformal wireless readout circuits to enable real‐time measurement of biomarkers in the sampled epidermal biofluids. The performance of the developed wearable device is demonstrated by measuring sweat‐alcohol and ISF‐glucose in human subjects consuming food and alcoholic drinks. The different compositions of sweat and ISF with good correlations of their chemical constituents to their blood levels make the developed platform extremely attractive for enhancing the power and scope of next‐generation noninvasive epidermal biosensing systems.

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Non-invasive wearable electrochemical sensors: a review

Cited by 1,040 publications

References 66 publications

Blending Electronics with the Human Body: A Pathway toward a Cybernetic Future

Blending Electronics with the Human Body: A Pathway toward a Cybernetic Future

Nanotechnologies for biomedical science and translational medicine

Simultaneous Monitoring of Sweat and Interstitial Fluid Using a Single Wearable Biosensor Platform

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