The inland aquaculture environment is an artificial ecosystem, where the water quality is a key factor which is closely related to the economic benefits of inland aquaculture and the quality of aquatic products. Compared with marine aquaculture, inland aquaculture is normally smaller and susceptible to pollution, with poor self-purification capacity. Considering its low cost and large-scale monitoring ability, many researches have developed spectrum sensor on-board satellite platforms to allow remote monitoring of inland water surface. However, there remain many problems, such as low image resolution, poor flexible data acquisition, and anti-interference. Apart from that, the conventional forecasting model is of weak generalization ability and low accuracy. In our study, we combine unmanned aerial vehicles system (UAVs) with the wireless sensor network (WSN) to design a new ground water quality parameter and drone spectrum information acquisition approach, and to propose a novel dynamic network surgery-deep neural networks (DNS-DNNs) model based on multi-source feature fusion to forecast the distribution of dissolved oxygen (DO) and turbidity (TUB) in inland aquaculture areas. The result of using fused features, including characteristic spectrum, Gray-level co-occurrence matrix (GLCM) texture feature, and convolutional neural network (CNN) texture feature to build a model is that the characteristic spectrum+ CNN texture fusion features were the best input items for DNS-DNNs when forecasting DO, with the determination coefficient R 2 of the vertical set arriving at 0.8741, while the characteristic spectrum+ GLCM texture+ CNN texture fusion features were the best for TUB, with the R 2 reaching 0.8531. Compared with a variety of conventional models, our model had a better performance in the inversion of DO and TUB, and there was a strong correlation between predicted and real values: R 2 reached 0.8042 and 0.8346, whereas the root mean square error (RMSE) were only 0.1907 and 0.1794, separately. Our study provides a new insight about using remote sensing to rapidly monitor water quality in inland aquaculture regions.