Non-Syndromic Familial Mesiodens: Presentation of Three Cases

Abstract

Mesiodens are the most common supernumerary teeth and are detected incidentally during routine radiographic examination, so late diagnosis complications are very common. The dentist must make a timely diagnosis and thus avoid clinical complications. Despite advances in knowledge of dental morphogenesis and differentiation, the etiology of mesiodens remains unclear. Therefore, several theories have been postulated to explain how and why they develop. It was described in the literature that heredity could play an important role in the appearance of supernumerary teeth, with a higher rate of appearance in relatives of those affected. This article reports three cases, a mother and two children, who present mesiodens, which shows that supernumerary teeth may involve a genetic factor. In addition, a literature review was carried out to assess the importance of the genetic factor as a possible cause of mesiodens. The relevance and implications of timely diagnosis in clinical practice to avoid manifestations of clinical complications are discussed. Therefore, the identification of the genetic risk factors responsible for the formation of supernumerary teeth is essential for developing a screening tool to determine an individual’s genetic risk.

Endodontic Treatment for a Mesiodens: A Case Report

“…The patient in this case mentioned his aunt and grandmother having a mesiodens tooth like him. In a study by Alarcón J. et al (2022), three cases were examined using CBCT to confirm the presence of inherited mesiodens, highlighting the hereditary nature of this dental anomaly [7]. Mesiodens were present for three generations in this case study, involving a grandmother, her daughter, and her grandson, highlighting the strong familial inheritance of genetic factors associated with mesiodens [7].…”

“…Extraction is the primary treatment for mesiodens due to the pathologies and alignment disturbances they cause in the dentition, which can lead to further complications if left untreated such as increased risks of infection, malocclusion, and damage to neighboring teeth [7][8][9]. Studies have consistently shown that mesiodens can lead to complications such as crowding, spacing issues, and the rotation of adjacent teeth, which can significantly impact dental alignment and function, according to the findings of these studies [1][2][3]9].…”

“…It causes malocclusion, like spacing, crowding, rotation of the adjacent tooth, and midline diastema [7][8][9].…”

“…It is impacted or partially erupted [7,11]. Ethically, we cannot extract a tooth without the patient's consent; if he wants to save it, we should consider it while planning his pain relief.…”

Nasopalatine Duct Cyst with Impacted Inverted Mesiodens: A Rare Case Report and Literature Review

“…Based on their appearance, mesiodens can be classified as rudimentary mesiodens and supplementary mesiodens in permanent and deciduous dentition, respectively. They are termed conical, tuberculate, or molariform based on their morphology [ 21 ].…”