Non-Union After Multiple Lumbar Fusion Surgeries in a Patient With Facioscapulohumeral Muscular Dystrophy: A Case Report and Review of the Literature

Total Hip Arthroplasty in a Patient With Fascioscapulohumeral Dystrophy

“…Analysis of myofibrils is mostly limited to Duchenne-type dystrophy, but patients with muscular dystrophy have decreased capacity for myocyte recovery as the breakdown of myofibrils cannot be fully compensated for by satellite cell proliferation [ 10 ]. As a result, muscle inflammation leads to necrosis with fibrotic remodeling and fatty cell replacement within muscle tissues [ 4 , 10 ], something that had been reportedly noted at one of the patient’s lumbar spine procedures. In cases where a DA approach was used, creatinine kinase levels have been found to be lower than those in cases where a posterior approach was used [ 7 ].…”

“…Her surgical history was significant for multiple failed spinal surgeries, complicated by hardware failure and delayed wound healing. The patient’s prior spinal hardware failure was believed to be the result of significant fatty infiltration and atrophy of the patients paraspinal muscles [ 4 ]. At initial presentation, she had limited household ambulatory ability with a rolling walker and was using a wheelchair for longer-distance ambulation.…”

Developing Mixed-Effects Models to Compare the Predictive Ability of Various Comorbidity Indices in a Contemporary Cohort of Patients Undergoing Lumbar Fusion

“…Despite established efficacy for well-selected patients, 3 lumbar spinal fusion can be associated with complications including postoperative infection, poor wound healing, intraoperative blood loss, postoperative hematoma, neurological deficit, cerebrospinal fluid leak, thromboembolism, injury to surrounding structures, adjacent segment degeneration, and nonunion potentially requiring reoperation. [4][5][6][7][8][9] Given these risks, a rigorous approach to operative patient selection is central to achieving optimal outcomes. Moreover, the implications of proper patient selection are not limited to the direct physical effects of surgery on the patient.…”

“…Despite established efficacy for well-selected patients, 3 lumbar spinal fusion can be associated with complications including postoperative infection, poor wound healing, intraoperative blood loss, postoperative hematoma, neurological deficit, cerebrospinal fluid leak, thromboembolism, injury to surrounding structures, adjacent segment degeneration, and nonunion potentially requiring reoperation. 4-9…”