Nonenzymatic Wearable Sensor for Electrochemical Analysis of Perspiration Glucose

Zhu, Xiaofei; Ju, Yinhui; Chen, Jian; Liu, Deye; Liu, Hong

doi:10.1021/acssensors.8b00168

Cited by 132 publications

(84 citation statements)

References 75 publications

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“…We have demonstrated in our previous work 6 that introducing a preconditioning step can solve issues related to peak suppression/overlap, by electrochemical cleaning of the electrode surface, creating defect sites through the removal of carbon or reducing various functional groups, which seems to be beneficial for the electrochemical response. Zhu et al 24 reported that an electrode pretreatment by applying a negative potential creates alkaline conditions near the electrode surface which may explain the increase and shift in the peak signal upon pretreatment at pH 7.0. To check if the strategy is applicable to heroin samples, SWV with a preconditioning step was performed at pH 7.0 and at pH 12.0.…”

Section: Electrochemical Screening Of Heroin and Mixing Agents At Ph 70mentioning

confidence: 99%

Electrochemical Strategies for Adulterated Heroin Samples

et al. 2019

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Electrochemical strategies to selectively detect heroin in street samples without the use of complicated electrode modifications were developed for the first time. For this purpose, heroin, mixing agents (adulterants, cutting agent and impurities) and their binary mixtures were subjected to square wave voltammetry measurements at bare graphite electrodes at pH 7.0 and pH 12.0, in order to elucidate the unique electrochemical fingerprint of heroin and mixing agents as well as possible interferences or reciprocal influences. Adjusting the pH from pH 7.0 to pH 12.0 allowed a more accurate detection of heroin in the presence of most common mixing agents. Furthermore, the benefit of introducing a preconditioning step prior to running square wave voltammetry on the electrochemical fingerprint enrichment was explored. Mixtures of heroin with other drugs (cocaine, 3,4-methylenedioxymethamphetamine and morphine) were also tested to explore the possibility of their discrimination and simultaneous detection. The feasibility of the proposed electrochemical strategies was tested on realistic heroin street samples from forensic cases, showing promising results for fast, on-site detection tools of drugs of abuse.

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Section: Electrochemical Screening Of Heroin and Mixing Agents At Ph 70mentioning

confidence: 99%

Electrochemical Strategies for Adulterated Heroin Samples

et al. 2019

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“…Non-enzymatic electrochemical glucose sensors possess the advantages over enzymatic sensors in terms of low cost, good thermal stability and satisfactory reproducibility 21,22 . Non-enzymatic electrochemical detection sensor is based on the oxidize glucose to a detectable electrochemical signal, which directly occurs on the electrode surface by an electric current effect 23 . For the non-enzymatic glucose sensor, the design and fabrication of the active materials play a key role in the sensing performances since it can efficiently catalyze and oxidize glucose to produce gluconolactone and can free from the operating conditions 24,25 .…”

Section: Introductionmentioning

confidence: 99%

Fabrication of porous NiMn2O4 nanosheet arrays on nickel foam as an advanced sensor material for non-enzymatic glucose detection

Zhang

Sun

et al. 2019

Sci Rep

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In this work, porous NiMn2O4 nanosheet arrays on nickel foam (NiMn2O4 NSs@NF) was successfully fabricated by a simple hydrothermal step followed by a heat treatment. Porous NiMn2O4 NSs@NF is directly used as a sensor electrode for electrochemical detecting glucose. The NiMn2O4 nanosheet arrays are uniformly grown and packed on nickel foam to forming sensor electrode. The porous NiMn2O4 NSs@NF electrode not only provides the abundant accessible active sites and the effective ion-transport pathways, but also offers the efficient electron transport pathways for the electrochemical catalytic reaction by the high conductive nickel foam. This synergy effect endows porous NiMn2O4 NSs@NF with excellent electrochemical behaviors for glucose detection. The electrochemical measurements are used to investigate the performances of glucose detection. Porous NiMn2O4 NSs@NF for detecting glucose exhibits the high sensitivity of 12.2 mA mM−1 cm−2 at the window concentrations of 0.99–67.30 μM (correlation coefficient = 0.9982) and 12.3 mA mM−1 cm−2 at the window concentrations of 0.115–0.661 mM (correlation coefficient = 0.9908). In addition, porous NiMn2O4 NSs@NF also exhibits a fast response of 2 s and a low LOD of 0.24 µM. The combination of porous NiMn2O4 nanosheet arrays and nickel foam is a meaningful strategy to fabricate high performance non-enzymatic glucose sensor. These excellent properties reveal its potential application in the clinical detection of glucose.

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“…For the majority of molecules and ions in body fluids, electrochemical approaches are commonly employed. To detect the concentration of some molecules, such as glucose, [ 30 ] alcohol, [ 31 ] and lactate, [ 32 ] the corresponding enzymes (i.e., glucose oxidase, alcohol oxidase, and lactate oxidase) act as the sensing elements via the specific reaction. The enzymes catalyze the zymolyte, during which electron transfer would happen.…”

Section: Basic Composition Of Wearable Sensorsmentioning

confidence: 99%

Recent Advances in Nanomaterial‐Enabled Wearable Sensors: Material Synthesis, Sensor Design, and Personal Health Monitoring

Peng

Zhao

Ping

et al. 2020

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166

105

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Wearable sensors have gained much attention due to their potential in personal health monitoring in a timely, cost‐effective, easy‐operating, and noninvasive way. In recent studies, nanomaterials have been employed in wearable sensors to improve the sensing performance in view of their excellent properties. Here, focus is mainly on the nanomaterial‐enabled wearable sensors and their latest advances in personal health monitoring. Different kinds of nanomaterials used in wearable sensors, such as metal nanoparticles, carbon nanomaterials, metallic nanomaterials, hybrid nanocomposites, and bio‐nanomaterials, are reviewed. Then, the progress of nanomaterial‐based wearable sensors in personal health monitoring, including the detection of ions and molecules in body fluids and exhaled breath, physiological signals, and emotion parameters, is discussed. Furthermore, the future challenges and opportunities of nanomaterial‐enabled wearable sensors are discussed.

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Nonenzymatic Wearable Sensor for Electrochemical Analysis of Perspiration Glucose

Cited by 132 publications

References 75 publications

Electrochemical Strategies for Adulterated Heroin Samples

Electrochemical Strategies for Adulterated Heroin Samples

Fabrication of porous NiMn2O4 nanosheet arrays on nickel foam as an advanced sensor material for non-enzymatic glucose detection

Recent Advances in Nanomaterial‐Enabled Wearable Sensors: Material Synthesis, Sensor Design, and Personal Health Monitoring

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