Nonrigid registration method to assess reproducibility of breath-holding with ABC in lung cancer

Feasibility of the use of the Active Breathing Co ordinator™ (ABC) in patients receiving radical radiotherapy for non-small cell lung cancer (NSCLC)

“…However we have found in a previous study that lung cancer patients can maintain an average breath hold time of 20 seconds [15]. Although there are studies that report the treatment of lung cancer patients with ABC, reproducibility rather than feasibility was the focus [16,17]. In this study we test the feasibility of treating NSCLC patients with radical radiotherapy using ABC.…”

Defining the margins in the radical radiotherapy of non-small cell lung cancer (NSCLC) with active breathing control (ABC) and the effect on physical lung parameters

“…Two strategies to compensate for tumour movement have evolved. The first aims to reduce internal respiration induced movement by maintaining a breath-hold, either actively or passively [14][15][16][17] . The second allows the patient to breathe freely with RT delivery either synchronised during a pre-defined phase of the respiratory cycle or continuously delivered while tracking the tumour [18][19][20] .…”

Frameless Stereotactic Radiosurgery of a Solitary Liver Metastasis Using Active Breathing Control and Stereotactic Ultrasound

“…Given the reproducibility of ABC ® immobilization in comparison to free breathing (about 4-6 mm [4,26,27,29]), residual error after EPID-based positional correction around 3 mm [6], the published data on the precision of BAT ® in the abdomen (ranging around 3 mm [7,8]) and our own experience with ABC ® and BAT ® , the estimated combined setup error when using both methods has the potential to match the precision of non-image-guided immobilization In this particular case, where the treated lesion was so small and so close to the diaphragm that it could not directly be visualized with ultrasound, positioning of the liver was used as the surrogate for positioning of the lesion. By this, however, surrogacy is taken to a superior level when compared to the usual approach in radiotherapy when bony anatomy acts as the target's surrogate.…”