2013
DOI: 10.1097/aog.0b013e3182839e0e
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Nonsurgical Management of Heavy Menstrual Bleeding

Abstract: Objective To compare the effectiveness of non-surgical abnormal uterine bleeding (AUB) treatments for bleeding control, quality of life, pain, sexual health, patient satisfaction, additional treatments needed, and adverse events. Data Sources MEDLINE and Cochrane databases from inception to May 2012. We included randomized controlled trials of non-surgical treatments for AUB. Interventions included the levonorgestrel intrauterine system, combined oral contraceptives, progestins, nonsteroidal anti-inflammator… Show more

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Cited by 132 publications
(75 citation statements)
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“…TSH levels were advised to rule out occult hypothyroidism. Pap smears were taken and endometrial biopsy was taken [9]. The drug was administered orally in the form of 60 mg tablet twice weekly (every Sunday and Thursday) for the first 12 weeks and then once a week (every Sunday) for another 12 week.…”
Section: Methodsmentioning
confidence: 99%
“…TSH levels were advised to rule out occult hypothyroidism. Pap smears were taken and endometrial biopsy was taken [9]. The drug was administered orally in the form of 60 mg tablet twice weekly (every Sunday and Thursday) for the first 12 weeks and then once a week (every Sunday) for another 12 week.…”
Section: Methodsmentioning
confidence: 99%
“…However, data concerning treatment of patients, women with AUB presumed secondary to ovulatory dysfunction (AUB-O), are limited [5]. There are no randomized trials that evaluated the use of hormonal therapy specifically for the treatment of AUB-O [11].…”
Section: Summary Of First Line Laboratory Tests For Abnormal Uterine mentioning
confidence: 99%
“…In 2013, the Society of Gynecologic Surgeons Systematic Review Group published a review of 22 studies comparing non-surgical therapy for the treatment of AUB presumed due to endometrial dysfunction (AUB-E) [5].…”
Section: Aub-ementioning
confidence: 99%
“…1 Similarly, authors of a recent systemic review on nonsurgical management of heavy menstrual bleeding recommend the use of the levonorgestrel intrauterine system over oral contraceptive pills (OCPs), luteal-phase progestins, and NSAIDs for the reduction of blood loss in women with heavy menstrual bleeding. 27 Based on the compelling evidence of overall efficacy and safety from numerous clinical trials, use of LNG-IUS can be considered as the first line therapy for Indian patients with heavy menstrual bleeding ( Figure 5). …”
Section: Place For the Use Of Lng-ius In Idiopathic Abnormal Uterine mentioning
confidence: 99%