Nontraditional Risk Factors for Obesity in Modern Society

Han, Su-Jin; Lee, Seung‐Hwan

doi:10.7570/jomes21004

Cited by 13 publications

(10 citation statements)

References 88 publications

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“…We hypothesize the results of our study support the hypothesis that the prevalence of obesity, besides being well-known, may be supported by several many lesser-known environmental factors that act in parallel [ 62 ].…”

Section: Discussionsupporting

confidence: 78%

Risk of Abdominal Obesity Associated with Phthalate Exposure of Nurses

Kolena

Hlisníková

Kečkéšová

et al. 2022

Toxics

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Background: Occupational health hazards associated with phthalate exposure among nurses are still not well understood. Methods: We used high-performance liquid chromatography and tandem mass spectrometry to analyze phthalates. Anthropometric measurements and questionnaires were conducted. Results: We observed associations between mono-benzyl phthalate (MBzP) and body mass index (BMI), hip circumference (HC), waist circumference (WC), waist to height ratio (WHtR), and fat mass index (FMI), visceral fat content, BMI risk and hip index risk (HIrisk), adjusted to consumer behavior and consumer practices (r = 0.36–0.61; p ≤ 0.046). In the same model, we detected an association between mono-n-butyl phthalate (MnBP) and waist to hip ratio (WHR; r = 0.36; p = 0.046), mono-carboxy-isononyl phthalate (cx-MiNP) and BMI (r = 0.37; p = 0.043), HC (r = 0.4; p = 0.026) and WHtR (r = 0.38; p = 0.037), between mono-oxo-isononyl phthalate oxo (MiNP) and HC (r = 0.36; p = 0.045), mono-2-ethylhexyl phthalate (MEHP), mono(2-ethyl-5-oxohexyl) phthalate (oxo-MEHP) and HIrisk (r = 0.38–0.41; p ≤ 0.036), between oxo-MEHP and Anthropometric Risk Index (ARI risk; r = 0.4; p = 0.028). We detected a relationship between BMI and MBzP (β = 0.655; p < 0.001) and mono-2-ethylhexyl phthalate (MEHP; β = −0.365; p = 0.003), between hip circumference and MBzP (β = 0.486; p < 0.001), MEHP (β = −0.402; p = 0.001), and sum of secondary metabolites of diisononyl phthalate (∑DiNP; β = 0.307; p = 0.016). We observed a relationship between fat content and MBzP (β = 0.302; p = 0.033), OH-MnBP (β = −0.736; p = 0.006) and MiBP (β = 0.547; p = 0.046), visceral fat content and MBzP (β = 0.307; p = 0.030), HI-risk and MBzP (β = 0.444; p = 0.001), ARI-risk and sum of di-n-butyl phthalate metabolites (∑DnBP; β = 0.337; p = 0.018). We observed an association between the use of protective equipment with cx-MiNP. Conclusions: Occupational exposure to phthalates may induce abdominal obesity and result in obesity-related metabolic disorders.

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Section: Discussionsupporting

confidence: 78%

Risk of Abdominal Obesity Associated with Phthalate Exposure of Nurses

Kolena

Hlisníková

Kečkéšová

et al. 2022

Toxics

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“…It is strongly recommended to further study the effect of multivitamin use and its association with precocious puberty. 27 , 28 …”

Section: Discussionmentioning

confidence: 99%

Increased Incidence of Precocious Puberty in Girls During COVID-19 Pandemic: Early Indicator of the Upcoming Childhood Metabolic Syndrome Pandemic?

Itani

Hamdan

Zgheib

et al. 2022

Global Pediatric Health

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To evaluate retrospectively the incidence of central precocious puberty (CPP) during the COVID 19 lockdown and comparing the data with the corresponding data from the previous 2 years. The study included 23 girls with CPP and 14 patients with early puberty. Nineteen patients were newly diagnosed with CPP compared to 4 patients diagnosed with CPP during the previous 2 years. The number of new patients diagnosed with CPP was significantly higher than the mean during the previous 2 years ( P < .001). There were more overweight patients with CPP during and after the lockdown ( P < .05). These patients had also increased uterus length ( P < .05) and more advanced bone age ( P < .05). The increase in the incidence of central precocious puberty during and after the lockdown due to COVID 19 can be considered a serious consequence of the increased fat mass and an early indicator of the worsening of childhood obesity.

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“…Noteworthy, social determinants of health, constituted by social, psychosocial and economic factors influencing health, exert a relevant role in the pathogenesis of CVD risk and morbi‐mortality. Several of the underlying physiological mechanisms linking development of CVD to social determinants of health have been analysed, and encompass inflammation, elevated stress hormones, immune cell activation, and cellular aging 40–42 …”

Section: The Need Of a Paradigm Shiftmentioning

confidence: 99%

“…Several of the underlying physiological mechanisms linking development of CVD to social determinants of health have been analysed, and encompass inflammation, elevated stress hormones, immune cell activation, and cellular aging. [40][41][42] Transformation is part of the clinical profession, and it is the clinicians' responsibility to look for better ways to care for patients. Although transforming care delivery can feel intimidating, to be successful clinicians need the skills to develop trusting relationships with patients at the same time as sharing evidence-based knowledge with colleagues.…”

Section: Shiftmentioning

confidence: 99%