Nontyphoidal Salmonella septic arthritis in an immunocompetent child – An atypical presentation highlighting the importance of definitive diagnosis

Lim, Lisi Elizabeth; Dowdle, Benjamin; Gardiner, Douglas

doi:10.1016/j.idh.2017.04.001

Cited by 3 publications

(2 citation statements)

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“…[ 35 ] It usually occurs in immunocompromised, but there have been reports in immunocompetent children. [ 35 36 ] We isolated three cases of NTS from septic arthritis. All of them were immunosuppressed, two patients with SLE and ALL in one patient.…”

Section: Discussionmentioning

confidence: 99%

Extraintestinal infections caused by nontyphoidal Salmonella from a tertiary care center in India

et al. 2018

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BACKGROUND: Infection with Salmonella has become an increasing problem worldwide. Recently, nontyphoid Salmonella (NTS) has become a global concern causing threat to the health of human. It causes gastrointestinal infection which may be self-limiting, but invasive infections may be fatal, requiring appropriate therapy. This study was done to analyze the spectrum of NTS infections causing extraintestinal infections and its susceptibility pattern from a tertiary care center in India. MATERIALS AND METHODS: The medical records of 27 patients whose cultures were positive for NTS between the years 2013–2016 were included in this retrospective study. The relevant demographic, clinical, and laboratory data were analyzed. RESULTS: Among the 27 patients, predominant patients were in the age group of 20–30 years. The male to female ratio is 1.7:1. Salmonella typhimurium was the predominant NTS isolated among 15/27 (55.5%), followed by Salmonella enteritidis 4/27 (14.8%). 18/27 (66.6%) of NTS were isolated from blood. Nalidixic acid was sensitive in 2/15 of S. typhimurium, 2/4 of S. enteritidis and 1/3 of Salmonella weltevreden, while others are nalidixic acid-resistant implying resistance to quinolones. They were sensitive to other antibiotics reported. CONCLUSION: This study highlights the spectrum of NTS causing extraintestinal infections which is an emerging infection occurring mostly in immunosuppressed individuals. There should be a high degree of clinical suspicion which would help in the early diagnosis and management of patients.

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Section: Discussionmentioning

confidence: 99%

Extraintestinal infections caused by nontyphoidal Salmonella from a tertiary care center in India

et al. 2018

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“…Similar to this case, most salmonella septic arthritis are monoarticular and the knee is the second most common joint affected after the hip joint. The synovium is a particular metastatic focus of salmonella infection [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

A rare case of septic arthritis of the knee caused by Salmonella typhi with preexisting typhoid fever in a healthy, immunocompetent child – A case report

Kurniawan

Sitorus

Loho

et al. 2021

International Journal of Surgery Case Reports

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Introduction Septic arthritis is a rapid and progressive infection caused by invasion of bacteria into the synovial joint. Disease of the joint causedby Salmonella spp in healthy children is an unusual event, with an estimated incidence of 0.1 to 0.2% of septic arthritis cases among children. The incidence of knee septic arthritis caused by Salmonella typhi with preexisting typhoid fever is very rare. Method We reported a case of 2-years old boy with a history of saddle-type fever 2 weeks prior to right knee pain. Typhoid fever was confirmed by immunoassay test. Knee septic arthritis was established from clinical findings, increased CRP level, ultrasonography, and joint aspiration. Culture of the aspirate subsequently grew Salmonella typhi . This case report had been reported in line with SCARE criteria. Result Arthrotomy and debridement were immediately performed.Intravenous piperacillin tazobactam was given for 6 days and replaced by amoxicillin clavulanic acid after the culture and sensitivity test was available. Patient recovered completely 5 months post surgery and showed excellence result with normal range of knee joint motion. Conclusion This case report suggests that any episode of joint swelling following preexisting typhoid fever should arise the physician’s awareness toward the possibility of septic arthritis and warrant immediate as well as proper management.

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Infection, Disease & Health for today, tomorrow, and the future

Mitchell

Shaban

2018

Infection, Disease & Health

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Nontyphoidal Salmonella septic arthritis in an immunocompetent child – An atypical presentation highlighting the importance of definitive diagnosis

Cited by 3 publications

References 9 publications

Extraintestinal infections caused by nontyphoidal Salmonella from a tertiary care center in India

Extraintestinal infections caused by nontyphoidal Salmonella from a tertiary care center in India

A rare case of septic arthritis of the knee caused by Salmonella typhi with preexisting typhoid fever in a healthy, immunocompetent child – A case report

Infection, Disease & Health for today, tomorrow, and the future

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