Normal fasting plasma glucose levels during pregnancy: a hospital-based study

Riskin-Mashiah, Shlomit; Damti, Amit; Younes, Grace; Auslander, Ron

doi:10.1515/jpm.2010.142

Cited by 43 publications

(32 citation statements)

References 10 publications

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“…There are reasonable clinical data suggesting that second trimester glucose metabolism is well correlated with maternal physiology in both first trimester and the pre-conception period 15–17 . However measurements of glucose, insulin, insulin resistance and clinical correlates from the time period encompassing pre-conception and the first trimester in mothers carrying infants affected with CHD are necessary to confirm the observed associations.…”

Section: Discussionmentioning

confidence: 96%

Maternal Midpregnancy Glucose Levels and Risk of Congenital Heart Disease in Offspring

et al. 2015

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IMPORTANCE There is a well-described association between maternal diabetes mellitus and risk of congenital heart disease (CHD) in offspring. Although the clinical diagnoses of type 2 diabetes or gestational diabetes are strong risk factors for CHD, subclinical abnormalities of glucose and insulin metabolism are common within the general population and could also confer risk for CHD. We hypothesize that continuous measures of blood analytes related to maternal diabetes are related to odds of cardiac malformations. OBJECTIVE To explore the potential association of 2 different CHD phenotypes in offspring with maternal midpregnancy measures of glucose and insulin. DESIGN, SETTING, AND PARTICIPANTS Case-control study from a population-based cohort of 277 pregnant women in southern and central California carrying infants with tetralogy of Fallot (TOF) (n = 55), dextrotransposition of the great arteries (dTGA) (n = 42), or healthy infants without CHD (n = 180). Serum samples were collected from 2003 through 2007. The analysis was conducted from March through June 2015.MAIN OUTCOMES AND MEASURES Blood analytes related to maternal glucose metabolism were measured from random nonfasting second-trimester blood samples. We measured serum insulin levels by a validated radioimmunoassay, and we measured glucose levels. Multivariable logistic regression models estimated the association between these levels and case status.

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Section: Discussionmentioning

confidence: 96%

Maternal Midpregnancy Glucose Levels and Risk of Congenital Heart Disease in Offspring

et al. 2015

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“…Riskin‐Mashiah et al . also proposed that the same cut‐off fasting PG value of 92–125 mg/dL could be used for GDM diagnosis throughout pregnancy. However, Cosson et al .…”

Section: Discussionmentioning

confidence: 99%

Difference in the prevalence of gestational diabetes mellitus according to gestational age at 75‐g oral glucose tolerance test in Japan: The Japan Assessment of Gestational Diabetes Mellitus Screening trial

Iwama

Sugiyama

Metoki

et al. 2019

J of Diabetes Invest

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Aims/IntroductionTo evaluate the differences in the results of 75‐g oral glucose tolerance tests (OGTTs) according to gestational age in Japan.Materials and MethodsIn this prospective cohort study, 2,578 pregnant women were divided into three categories based on their gestational age during the 75‐g OGTT: <14 weeks’ gestation, 14–23 weeks’ gestation and 24–32 weeks’ gestation. The association between gestational age and the results of the 75‐g OGTT were evaluated using multivariable analysis.ResultsEarly gestational age was associated with high fasting plasma glucose levels at the time of the 75‐g OGTT, and low corresponding 1‐h and 2‐h plasma glucose levels. Compared with women with a gestational age of 24–32 weeks, women who had undergone the 75‐g OGTT at <14 weeks’ gestation had significantly higher odds of gestational diabetes mellitus diagnosis based on the currently used criteria in Japan (adjusted odds ratio 1.42, 95% confidence interval 1.07–1.90).ConclusionsThe results of the 75‐g OGTT varied by gestational age. The use of the same 75‐g OGTT cut‐off values for the diagnosis of gestational diabetes mellitus, regardless of gestational age, might lead to increases in the prevalence of gestational diabetes mellitus diagnosis in Japan.

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“…Indeed, FPG levels decrease early in pregnancy with only a slight further decrease later on [28]. However, the concordance between early and late GDM diagnosis is imperfect.…”

Section: Issues and Proposals For Screening During Early Pregnancymentioning

confidence: 99%

Screening for dysglycaemia during pregnancy: Proposals conciliating International Association of Diabetes and Pregnancy Study Group (IADPSG) and US National Institutes of Health (NIH) panels

Cosson

Valensi

Carbillon

2015

Diabetes & Metabolism

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Normal fasting plasma glucose levels during pregnancy: a hospital-based study

Abstract: Fasting glucose levels decrease early in pregnancy with only slight further decrease later on. It seems that the same fasting glucose cut-off can be used throughout pregnancy for the diagnosis of gestational diabetes mellitus.

Cited by 43 publications

References 10 publications

Maternal Midpregnancy Glucose Levels and Risk of Congenital Heart Disease in Offspring

Maternal Midpregnancy Glucose Levels and Risk of Congenital Heart Disease in Offspring

Difference in the prevalence of gestational diabetes mellitus according to gestational age at 75‐g oral glucose tolerance test in Japan: The Japan Assessment of Gestational Diabetes Mellitus Screening trial

Screening for dysglycaemia during pregnancy: Proposals conciliating International Association of Diabetes and Pregnancy Study Group (IADPSG) and US National Institutes of Health (NIH) panels

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