Normal reference values of three‐dimensional speckle‐tracking echocardiography‐derived right atrial volumes and volume‐based functional properties in healthy adults (Insights from the MAGYAR‐Healthy Study)

Abstract

Introduction: The right atrium (RA) roles include being a systolic reservoir, an early diastolic conduit, and a late-diastolic booster pump. The present study aimed to assess normal reference values of three-dimensional speckle-tracking echocardiography (3DSTE)-derived RA volumetric data and volume-based functional properties in healthy adult subjects. Methods: We included 260 healthy adult subjects in sinus rhythm with complete clinical and demographic dataset, but excluded 110 of them because of inferior image quality. The remaining population sample comprised 150 subjects (31.0 ± 11.6 years, 79 males). Complete two-dimensional Doppler echocardiography and 3DSTE have been performed in all subjects.Results: Systolic RA volumetric variables did not show changes over time, but after 50 years, a significant reduction could be demonstrated in RA stroke volume and emptying fraction. While early diastolic RA volume increased over time, RA stroke volume and emptying fraction decreased. While late-diastolic RA volume increased over age decades, similar increase could be detected in RA stroke volume but a reduction occurred in older ages. Late-diastolic RA emptying fraction showed an increasing (after the 40s)-decreasing (after the 50s) pattern. Conclusions:Our study provides normal reference values of 3DSTE-derived RA volumes and volume-based functional properties and their age-and gender dependency in healthy adult subjects. K E Y W O R D S echocardiography, healthy subjects, right atrium, speckle-tracking, three-dimensional

Normal reference values of three‐dimensional speckle‐tracking echocardiography‐derived mitral annular dimensions and functional properties in healthy adults: Insights from the MAGYAR‐Healthy Study

“…Moreover, the results can only be applied to the Toshiba equipment we used. As mentioned above, only 2D MA projection was evaluated during 3DSTE analysis, not its real 3D saddle shape 10 The present study did not aim to compare 2D‐ and 3DSTE‐derived MA dimensions. We included a limited number of cases older than 50 years, and none over 60 years. Although 3DSTE could combine volumetric and strain assessments allowing more detailed analysis from the same 3D echocardiographic dataset 3‐8 for MA featuring, no volumes or strains of other heart chambers were assessed in the present study. …”

“…• Although 3DSTE could combine volumetric and strain assessments allowing more detailed analysis from the same 3D echocardiographic dataset [3][4][5][6][7][8] for MA featuring, no volumes or strains of other heart chambers were assessed in the present study.…”

“…along the cardiac cycle. 1,2 More and more 3DSTE-based clinical data are available in different pathological conditions together with normal reference values of left ventricular (LV), [3][4][5] left atrial (LA), 6 and right atrial (RA) 7,8 volumes/volume-based functional properties, 8 strains, 3,4,6,7 and rotational variables 5 in healthy adults, as well as their vendor-dependency. 9 Moreover, the clinical usefulness of 3DSTE in the assessment of mitral annular dimensions and its close relationship to LV function was also confirmed.…”

Tricuspid annular abnormalities following different surgical strategies in adults with corrected tetralogy of Fallot (Results from the CSONGRAD Registry and MAGYAR-Path Study)

“…For measurement of RA volumetric parameters, a 3D model of the RA was created by using the same software demonstrated in recent studies (13)…”

Normal reference values of left ventricular strain parameters in healthy adults: Real‐life experience from the single‐center three‐dimensional speckle‐tracking echocardiographic MAGYAR‐Healthy Study

“…3D STE (3DSTE) incorporates advantages of both 3D and STE methodologies: it is able to simultaneously assess volumes and functional (strain) variables from the same 3D dataset 1‐6 . A number of studies defining normal values of 3DSTE‐derived parameters is presently available, including left ventricular (LV), 9‐14 left atrial, 15 and right atrial 16,17 volumetric, 17 strain, 10–12,14 and rotational data 9,10,13 . The present prospective study aimed to quantify normal reference values of LV strains in healthy adult population in real clinical world settings in different age groups and to determine age‐ and gender‐dependence of these variables in a high volume single center.…”