Normal values of liver elasticity measured by real-time tissue elastography (RTE) in healthy infants and children

Selmi, Buket; Engelmann, Guido; Teufel, Ulrike; Sakka, Saroa El; Dadrich, Monika; Schenk, Jens‐Peter

doi:10.1007/s10396-013-0465-0

Cited by 11 publications

(6 citation statements)

References 40 publications

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“…2 Normal values of liver elasticity in healthy children were reported by Selmi et al, but they did not evaluate the kidneys and spleen, and newborns and infants were not included. 3 Shear wave elastography values for the liver, kidney, and spleen in normal newborns and infants are required as reference data, and to the best of our knowledge, our study is the first report on this subject.…”

Section: Discussionmentioning

confidence: 97%

Evaluation of Liver, Kidney, and Spleen Elasticity in Healthy Newborns and Infants Using Shear Wave Elastography

Palabıyık

İnci

Türkay

et al. 2017

J of Ultrasound Medicine

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Section: Discussionmentioning

confidence: 97%

Evaluation of Liver, Kidney, and Spleen Elasticity in Healthy Newborns and Infants Using Shear Wave Elastography

Palabıyık

İnci

Türkay

et al. 2017

J of Ultrasound Medicine

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“…If there is no change in aminotransferase levels after 6 mo, a liver biopsy should be performed. Non-invasive liver stiffness measurement can be used for follow-up after liver biopsy if the stage of fibrosis has been determined based on histopathological criteria[77]. …”

Section: Discussionmentioning

confidence: 99%

Limitations and opportunities of non-invasive liver stiffness measurement in children

Engelmann¹,

Quader²,

Teufel³

et al. 2017

WJH

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Changes in liver structure are an important issue in chronic hepatopathies. Until the end of the 20th century, these changes could only be determined by histological analyses of a liver specimen obtained via biopsy. The well-known limitations of this technique (i.e., pain, bleeding and the need for sedation) have precluded its routine use in follow-up of patients with liver diseases. However, the introduction of non-invasive technologies, such as ultrasound and magnetic resonance imaging, for measurement of liver stiffness as an indirect marker of fibroses has changed this situation. Today, several non-invasive tools are available to physicians to estimate the degree of liver fibrosis by analysing liver stiffness. This review describes the currently available tools for liver stiffness determination that are applicable to follow-up of liver fibrosis/cirrhosis with established clinical use in children, and discusses their features in comparison to the “historical” tools.

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“…It should be point out that results also vary when different facilities or probes are used to measure liver stiffness. 2D-SWE is highly effective in diagnosing liver fibrosis, in which results are not affected by the size of the ROI, age, or BMI [33]. However, the depth of the sampling frame and different segments of the liver show significant influences.…”

Section: Clinical Applicationmentioning

confidence: 99%

Ultrasound Elastography in Liver Tissue: Current Status

Zhang¹,

Ding²,

Niu³

et al. 2021

Advanced Ultrasound in Diagnosis and Therapy

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Chronic liver disease is common in China and worldwide, with liver fibrosis as the primary pathological finding.Any chronic liver disease can lead to hepatic fibrosis and gradually develop into cirrhosis. Complications, such as portal hypertension, gastrointestinal bleeding, and liver failure can occur. Some patients even develop hepatocellular carcinoma. Thus, timely diagnosis of hepatic fibrosis is vital for the assessment of etiology, treatment, and prognosis. Conventional ultrasound imaging shows low sensitivity with its subjectivity for preliminary diagnosis of liver fibrosis, creating limitations in qualitative and quantitative evaluation. Ultrasound elastography is a recently developed technique that can help overcome these limitations.The elastic imaging method combines conventional ultrasound to assess liver stiffness along with routine examination. This "one-stop" check for liver disease opens new prospects for clinical and scientific research and improves the accuracy of disease diagnosis for broad clinical application. This article will review the current status of ultrasound elastography for its applications in chronic liver diseases.

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Normal values of liver elasticity measured by real-time tissue elastography (RTE) in healthy infants and children

Abstract: Real-time elastography is a new sonography-based method and may be used as a supportive analysis to assess liver parenchyma elasticity in children, especially when fibrosis is suspected. We measured RTE normal values in children as reference data.

Cited by 11 publications

References 40 publications

Evaluation of Liver, Kidney, and Spleen Elasticity in Healthy Newborns and Infants Using Shear Wave Elastography

Evaluation of Liver, Kidney, and Spleen Elasticity in Healthy Newborns and Infants Using Shear Wave Elastography

Limitations and opportunities of non-invasive liver stiffness measurement in children

Ultrasound Elastography in Liver Tissue: Current Status

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