Nosocomial Gram‐positive bacterial infections in children: Results of a 7 year study

Çelebi, Solmaz; Hacımustafaoğlu, Mustafa; Özdemır, Özlem; Özakın, Cüneyt

doi:10.1111/j.1442-200x.2007.02485.x

Cited by 18 publications

(15 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, similar to findings reported by Celebi et al 16 , clinical improvement was documented in more than half of the infants. The CoNS isolate represented true bacteremia and all study patients met the clinical criteria for sepsis.…”

Section: Discussionsupporting

confidence: 90%

Nosocomial infections in a Brazilian neonatal intensive care unit: a 4-year surveillance study

Brito

Resende

et al. 2010

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Introduction: Report the incidence of nosocomial infections, causative microorganisms, risk factors associated with and antimicrobial susceptibility pattern in the NICU of the Uberlândia University Hospital. Methods‫׃‬ Data were collected through the National Healthcare Safety Network surveillance from January 2006 to December 2009. The patients were followed five times/week from their birth to their discharge or death. Results‫׃‬ The study included 1,443 patients, 209 of these developed NIs, totaling 293 NI episodes, principally bloodstream infections (203; 69.3%) and conjunctivitis (52; 17.7%). Device-associated infection rates were as follows: 17.3 primary bloodstream infections per 1,000 central line-days and 3.2 pneumonias per 1000 ventilator-days. The mortality rate in neonates with NI was 11.9%. Mechanical ventilation, total parenteral nutrition, orogastric tube, previous antibiotic therapy, use of CVC and birth weight of 751-1,000g appeared to be associated with a significantly higher risk of NI (p ≤ 0.05). In multiple logistic regression analysis for NI, mechanical ventilation and the use of CVC were independent risk factors (p ≤ 0.05). Coagulase-negative Staphylococcus (CoNS) (36.5%) and Staphylococcus aureus (23.6%) were the most common etiologic agents isolated from cultures. The incidences of oxacillin-resistant CoNS and S. aureus were 81.8% and 25.3%, respectively. Conclusions‫׃‬ Frequent surveillance was very important to evaluate the association of these well-known risk factors with NIs and causative organisms, assisting in drawing the attention of health care professionals to this potent cause of morbidity.

show abstract

Section: Discussionsupporting

confidence: 90%

Nosocomial infections in a Brazilian neonatal intensive care unit: a 4-year surveillance study

Brito

Resende

et al. 2010

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

show abstract

“…Most CoNS isolates recovered from infants in this study were resistant to oxacillin. Nevertheless, similar to fi ndings reported by Celebi et al 1 , clinical improvement was documented in more than half of the patients. The CoNS isolates represented true bacteremia, and all study patients met the clinical criteria for sepsis.…”

Section: Ethical Considerationssupporting

confidence: 90%

“…Newborns admitted to intensive care units (ICUs) are at high risk for developing nosocomial infections (NIs) because of the severity of their illness and exposure to invasive medical devices such as mechanical ventilators and central venous catheters (CVCs) and resistant microorganisms 1,2 . Surveillance of NIs is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries 3 .…”

Section: Introductionmentioning

confidence: 99%

Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012

Urzedo

Levenhagen

Pedroso

et al. 2014

Rev. Soc. Bras. Med. Trop.

View full text Add to dashboard Cite

Introduction: Surveillance of nosocomial infections (NIs) is an essential part of quality patient care; however, there are few reports of National Healthcare Safety Network (NHSN) surveillance in neonatal intensive care units (NICUs) and none in developing countries. The purpose of this study was to report the incidence of NIs, causative organisms, and antimicrobial susceptibility patterns in a large cohort of neonates admitted to the NICU during a 16-year period. Methods: The patients were followed 5 times per week from birth to discharge or death, and epidemiological surveillance was conducted according to the NHSN. Results: From January 1997 to December 2012, 4,615 neonates, representing 62,412 patient-days, were admitted to the NICU. The deviceassociated infection rates were as follows: 17.3 primary bloodstream infections per 1,000 central line-days and 3.2 pneumonia infections per 1,000 ventilator-days. A total of 1,182 microorganisms were isolated from sterile body site cultures in 902 neonates. Coagulase-negative staphylococci (CoNS) (34.3%) and Staphylococcus aureus (15.6%) were the most common etiologic agents isolated from cultures. The incidences of oxacillin-resistant CoNS and Staphylococcus aureus were 86.4% and 28.3%, respectively. Conclusions:The most important NI remains bloodstream infection with staphylococci as the predominant pathogens, observed at much higher rates than those reported in the literature. Multiresistant microorganisms, especially oxacillin-resistant staphylococci and gram-negative bacilli resistant to cephalosporin were frequently found. Furthermore, by promoting strict hygiene measures and meticulous care of the infected infants, the process itself of evaluating the causative organisms was valuable.

show abstract

“…In a study performed in Uludağ University Medical Faculty in 2003 where only culture results were evaluated, the rate of NI was found to be 12%. In İzmir, the frequency of confirmed sepsis was found to be 9.1% in newborns (12,13). In a multicenter surveillance study performed by the Turkish Neonatology Association, the frequency of sepsis raged between 2.2% and 17% (14).…”

Section: Introductionmentioning

confidence: 96%

Yenidoğan ve yenidoğan yoğun bakım servisinde hastane enfeksiyonları

Hacımustafaoğlu¹,

Çelebi²,

Köksal³

et al. 2011

tpa

View full text Add to dashboard Cite

Aim: Nosocomial infections (NI) in a neonatal intensive care unit (NICU) and neonatal clinic were evaluated during a one-year-period. Material and Method: 314 newborns were investigated for nosocomial infections. Local ethics committee approval was given for this study. Nosocomial infections was defined using the CDC criteria. Results: Nosocomial infections developed in 53% of 127 patients (58% with culture positivity) in the NICU and in 2.6% of 187 patients (all with a negative culture) in the neonatal clinic. In total, (NICU plus neonatal clinic), NI developed in 23% of hosptalized patients. Nosocomial infections rate was 42.3% and in terms of patient days, NI rate was 14/1000 patient-day. When evaluated separately, NI developed in 53.5% of patients admitted in NICU and in 2.6% of neonatal clinic patients. Also, NI rates were 17.9/1000 patient-day in NICU and 1.6/1000 patient-day in the neonatal clinic. Patients with NI stayed at the hospital for 73.6±47.8 day in NICU and for 16.0±6.7 day in the neonatal clinic. Nosocomial infections developed on the 29.4±30.9 th d in NICU and on the 7.6±2.9 th day in the neonatal clinic. In NICU, in terms of 128 NI episodes, the NI related mortality was 8.5%. 16.1% (n: 11) of the patients with NI died. They died on the 56.7±50.2 nd day of admission and on the 25.8±10.2 nd day second after NI diagnosis. There was no mortality in neonatal clinic patients. Conclusions: Our NI rates were slightly higher than the developed countries and lower than the developing countries. (Turk Arch Ped 2011; 46: 293-8)

show abstract

Nosocomial Gram‐positive bacterial infections in children: Results of a 7 year study

Abstract: In the present patients primary BSI were the most common nosocomial GP bacterial infections and CONS were the most frequent GP pathogen isolated. Antimicrobial resistance in GP isolates is an increasing problem.

Cited by 18 publications

References 34 publications

Nosocomial infections in a Brazilian neonatal intensive care unit: a 4-year surveillance study

Nosocomial infections in a Brazilian neonatal intensive care unit: a 4-year surveillance study

Nosocomial infections in a neonatal intensive care unit during 16 years: 1997-2012

Yenidoğan ve yenidoğan yoğun bakım servisinde hastane enfeksiyonları

Contact Info

Product

Resources

About