Notch ligand-expressing adenovirus infection enhances the efficacy of dendritic cell-based immunotherapy for allergic asthma in mice

Effects of simvastatin on immunoreaction and inflammation in rats with asthma by regulating NOTCH signaling pathway

“…The NOTCH signaling pathway, one of the important signal transduction pathways in the body, is considered to play a vital role in the pathogenesis and pathological responses of asthma, and it participates in the pathologi-cal responses of asthma by modulating immunoreaction and inflammation (3)(4)(5). It has been now considered that interferon-γ (INF-γ) regulated by the NOTCH signaling pathway is one of the key environments and leading causes of immunoreaction during asthma.…”