Notes by a naturalist : an account of observations made during the voyage of H.M.S. "Challenger" round the world in the years 1872-1876 / by H. N. Moseley.

Moseley, H. N.

doi:10.5962/bhl.title.14281

Cited by 30 publications

(29 citation statements)

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“…Peaks were integrated and the areas exported to Excel via the TraceFinder 3.3 (Thermo, http://Waltham,%20MA,%20USA) software package. Peak areas were corrected for natural abundance as previously described, after which fractional enrichment and μmoles metabolites per gram protein were calculated to quantify 13 C incorporation into various metabolites.…”

Section: Methodsmentioning

confidence: 99%

UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways

et al. 2019

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Uncoupling protein 2 (UCP2) is often upregulated in cancer cells. The UCP2 upregulation is positively correlated with enhanced proliferation, tumorigenesis, and metabolic alterations, thus suggesting that UCP2 upregulation could play a key role in sensing metabolic changes to promote tumorigenesis. To determine the global metabolic impact of UCP2 upregulation, we used 13C6 glucose as a source molecule to ‘trace’ the metabolic fate of carbon atoms derived from glucose. UCP2 overexpression in skin epidermal cells enhanced the incorporation of 13C-label to pyruvate, TCA cycle intermediates, nucleotides, and amino acids, suggesting that UCP2 upregulation reprograms cellular metabolism towards macromolecule synthesis. To the best of our knowledge, this is the first study to bring to light the overall metabolic differences caused by UCP2 upregulation.

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Section: Methodsmentioning

confidence: 99%

UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways

et al. 2019

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“…13 C‐3 acrylic acid (Cambridge Isotope Labs, 99 atom % 13 C, 0.1 % 4‐methoxyphenol) was fed (0.3 kPa) along with acrolein (1.5 kPa, unlabeled), O 2 (3.3 kPa), and water (4.8 kPa) during the isotopic labeling co‐feed batch reaction experiment. Isotopic content of carbon‐containing species was assessed via the method of Price and Iglesia, where mass spectra of unlabeled compounds were corrected for presence of natural 13 C abundance using the method described by Moseley . Natural abundances of 13 C 1 ‐labeled species were subtracted from observed 13 C 1 abundance and added to abundance of the unlabeled isotopologue.…”

Section: Methodsmentioning

confidence: 99%

“…Isotopic content of carbon-containing species was assessed via the method of Price and Iglesia, [31] where mass spectra of unlabeled compounds were corrected for presence of natural 13 C abundance using the method described by Moseley. [32] Natural abundances of 13 C 1 -labeled species were subtracted from observed 13 C 1 abundance and added to abundance of the unlabeled isotopologue.…”

Section: Methodsmentioning

confidence: 99%

Reaction Pathways in Acrolein Oxidation over a Mixed‐Oxide Catalyst

Miller

Bhan

2018

ChemCatChem

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A reaction network detailing the mechanistic origins of 17 C1−C7 byproducts in acrolein oxidation over a vanadium molybdate mixed oxide catalyst doped with antimony and copper is proposed based on measurements of acrolein oxidation rates with co‐feeds of C1−C7 organics formed as byproducts, acrylic acid 13C isotopic tracer experiments, and probe molecule reactions. C1 and C2 products form via C−C bond scission of either the single or double C−C bond in acrolein and acrylic acid. C4−C7 products form by addition of one or two acrolein or acrylic acid molecules to a C2 surface species coupled with decarbonylation or decarboxylation events. Two‐carbon ethyl and vinyl surface species and three‐carbon acrolein‐derived surface species are involved in all pathways that lead to byproduct formation; controlling the relative abundance and reactivity of such intermediates is integral to prescribing process conditions and material compositions for selective oxidation of acrolein.

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“…Moseley was part of the nineteenth century imperial, exploratory scientific tradition. He had served on the Challenger expedition (1873–6) as a zoologist, with subsidiary work in botany and ethnography (Moseley 1892). Moseley knew Charles Darwin (the Beagle expedition) and T.H.…”

Section: Early Trainingmentioning

confidence: 99%

The imperial vision of Halford Mackinder

Blouet¹

2004

Geographical Journal

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From 1899 to 1939, Halford Mackinder was active in imperial affairs. In 1899, the same year he climbed Mount Kenya, he set out the case for free trade. Rapidly he converted to imperial protectionism, left the Liberal Party and joined the Conservatives. Mackinder, along with his associates in the Conservative Party, Leo Amery and Lord Milner, promoted the cause of imperial unity and imperial preference in trade. During the period 1899–1903, Mackinder's evolving ideas about empire helped shape the Pivot paper, and he spelt out a prescription to avoid imperial decline: bind Britain and the Dominions into a League of Democracies with one fleet and one foreign policy, and encourage economic growth within the empire by a system of tariffs that promoted imperial trade. In Mackinder's parliamentary career (1910–22), his party was never in power and the Liberals retained free trade. Only after World War I, at the end of his parliamentary career, did Mackinder become active in imperial policy as chair of the Imperial Shipping Committee and the Imperial Economic Committee.

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Notes by a naturalist : an account of observations made during the voyage of H.M.S. "Challenger" round the world in the years 1872-1876 / by H. N. Moseley.

Cited by 30 publications

References 0 publications

UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways

UCP2 Overexpression Redirects Glucose into Anabolic Metabolic Pathways

Reaction Pathways in Acrolein Oxidation over a Mixed‐Oxide Catalyst

The imperial vision of Halford Mackinder

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