2012
DOI: 10.1159/000337860
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Novel Application of Theranekron® Enhanced the Structural and Functional Performance of the Tenotomized Tendon in Rabbits

Abstract: The effects of Tarantula cubensis extract (TC; Theranekron®) on the experimentally induced rupture of the superficial digital flexor tendon (SDFT) 28 days post-injury (DPI) was studied in rabbits. Forty mature White New Zealand male rabbits were randomly divided into two groups. TC was repeatedly injected subcutaneously over the lesion 3, 7 and 10 days after tenotomy and surgical anastomosis. Clinical and ultrasonographic evaluations were conducted at weekly intervals. The animals were euthanized 28 DPI and th… Show more

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Cited by 35 publications
(67 citation statements)
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“…Based on the anatomic position of these structures, extra synovial tendons are covered by paratenon and intrasynovial tendons and ligaments are covered by a synovium or synovial sheath ( Figure 1) [1][2][3]12]. In general tendons and ligaments have low cellularity consisting of mature fibroblast or tenoblasts and fibrocytes or tenocytes [1][2][3][4][5][6][7][8][9][10][11]. Thus, more than 90% of the dry matter of tendons and ligaments are collagenous in nature with a little cellularity and other tissue compositions such as glycosaminoglycans and elastic fibers [3,12].…”
Section: Structure Of Tendons and Ligamentsmentioning
confidence: 99%
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“…Based on the anatomic position of these structures, extra synovial tendons are covered by paratenon and intrasynovial tendons and ligaments are covered by a synovium or synovial sheath ( Figure 1) [1][2][3]12]. In general tendons and ligaments have low cellularity consisting of mature fibroblast or tenoblasts and fibrocytes or tenocytes [1][2][3][4][5][6][7][8][9][10][11]. Thus, more than 90% of the dry matter of tendons and ligaments are collagenous in nature with a little cellularity and other tissue compositions such as glycosaminoglycans and elastic fibers [3,12].…”
Section: Structure Of Tendons and Ligamentsmentioning
confidence: 99%
“…bone fixation using plating techniques; tissue dissection, etc.) [4][5][6][7][8]. In addition, these types of injuries have been reported to occur as a result of vehicular trauma [9][10][11].…”
Section: Tendon and Ligament Injuriesmentioning
confidence: 99%
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