Novel bayberry-and-honeycomb-like magnetic surface molecularly imprinted polymers for the selective enrichment of rutin from Sophora japonica

Song, Huijia; Hai-pin, Zhang; He, Yulian; Gao, Ruixia; Wang, Wenting; Pfefferle, Lisa D.; Tang, Xiaoshuang; Tang, Yuhai

doi:10.1016/j.foodchem.2021.129722

Cited by 54 publications

(21 citation statements)

References 37 publications

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“…The peculiar peak at 572 cm −1 found both in Fe 3 O 4 –COOH and D-mag-MIPs can be ascribed to Fe–O vibration. 40 The characteristic peaks at 3420 cm −1 and 1650 cm −1 are attributed to –OH and CO stretching vibrations, respectively, indicating the existence of carboxyl groups on the magnetic nanoparticles. After coating with the PEI imprinted layer (Fig.…”

Section: Resultsmentioning

confidence: 98%

Spatially-directed magnetic molecularly imprinted polymers with good anti-interference for simultaneous enrichment and detection of dual disease-related bio-indicators

et al. 2022

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Section: Resultsmentioning

confidence: 98%

Spatially-directed magnetic molecularly imprinted polymers with good anti-interference for simultaneous enrichment and detection of dual disease-related bio-indicators

et al. 2022

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“…[13,14] Rutin, a natural flavonoid, is extensively found in vegetables and fruit with no discernible toxicity and poor bioavailability in rodents, suggesting that rutin is a potential substrate of intestinal flora. [15][16][17] The pharmacological properties of rutin include, but not limited to, remarkable anti-inflammation and antioxidation. [16,18] Rutin can also improve abnormal body-weight growth and impaired glucose metabolism.…”

Section: Introductionmentioning

confidence: 99%

“…[15][16][17] The pharmacological properties of rutin include, but not limited to, remarkable anti-inflammation and antioxidation. [16,18] Rutin can also improve abnormal body-weight growth and impaired glucose metabolism. [15,[19][20][21] Nevertheless, the biological mechanisms underlying its antiobesity effect remain elusive.…”

Section: Introductionmentioning

confidence: 99%

Intestinal Flora Mediates Antiobesity Effect of Rutin in High‐Fat‐Diet Mice

Zhai

Zhou

et al. 2022

Molecular Nutrition Food Res

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Scope Intestinal flora plays a critical role in the development of . Rutin is a natural flavonoid with potential prebiotic effects on regulating the intestinal flora composition that is beneficial for host health. Therefore, this study hypothesizes that rutin supplementation has beneficial effects on high‐fat‐diet (HFD)‐induced obesity and metabolic disorder through the modulation of intestinal flora in mice. Methods and results The obesity‐alleviating property of rutin using 6‐week‐old C57BL/6J male mice fed on HFD with or without rutin supplementation for 16 weeks is investigated. Rutin supplementation effectively reduces body‐weight gain, insulin resistance, and acted favorably on the intestinal barrier, thereby reducing endotoxemia and systemic inflammation. Sequencing of 16S rRNA genes from fecal samples indicate that rutin exerted modulatory effects on HFD‐induced intestinal flora disorders (e.g., rutin decreased Firmicutes abundance and increased Bacteroidetes and Verrucomicrobia abundance). Antibiotic treatment and fecal microbiota transplantation further demonstrate that the salutary effects of rutin on obesity control are strongly dependent on the intestinal flora. Conclusion Rutin can be considered as a prebiotic agent for improving intestinal flora disorders and obesity‐associated metabolic perturbations in obese individuals.

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“…For the extraction of active components from natural products, most of them use core-shell molecularly imprinted polymers as adsorbents. Compared with conventional extraction methods, it has the advantages of higher stability, higher selectivity [ 17 ], and higher adsorption capacity [ 18 ]. If the magnetic material is introduced as the core, MIP can be separated from the sample solution quickly once using an external magnet.…”

Section: Introductionmentioning

confidence: 99%

Selective Recognition of Gallic Acid Using Hollow Magnetic Molecularly Imprinted Polymers with Double Imprinting Surfaces

Zhou

Yan

et al. 2022

Polymers

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Gallic acid is widely used in the field of food and medicine due to its diversified bioactivities. The extraction method with higher specificity and efficiency is the key to separate and purify gallic acid from complex biological matrix. Herein, using self-made core-shell magnetic molecularly imprinted polymers (MMIP) with gallic acid as template, a hollow magnetic molecularly imprinted polymer (HMMIP) with double imprinting/adsorption surfaces was prepared by etching the mesoporous silica intermediate layer of MMIP. The characterization and adsorption research showed that the HMMIP had larger specific surface area, higher magnetic response strength and a more stable structure, and the selectivity and saturated adsorption capacity (2.815 mmol/g at 318 K) of gallic acid on HMMIP were better than those of MMIP. Thus, in addition to MMIP, the improved HMMIP had excellent separation and purification ability to selectively extract gallic acid from complex matrix with higher specificity and efficiency.

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Novel bayberry-and-honeycomb-like magnetic surface molecularly imprinted polymers for the selective enrichment of rutin from Sophora japonica

Cited by 54 publications

References 37 publications

Spatially-directed magnetic molecularly imprinted polymers with good anti-interference for simultaneous enrichment and detection of dual disease-related bio-indicators

Spatially-directed magnetic molecularly imprinted polymers with good anti-interference for simultaneous enrichment and detection of dual disease-related bio-indicators

Intestinal Flora Mediates Antiobesity Effect of Rutin in High‐Fat‐Diet Mice

Selective Recognition of Gallic Acid Using Hollow Magnetic Molecularly Imprinted Polymers with Double Imprinting Surfaces

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