Novel butterfly-shaped AIE-active pyrrolopyrrole aza-BODIPYs: synthesis, bioimaging and diamine/polyamine detection

Abstract

Constructing novel near-infrared (NIR) fluorophores with aggregation-induced emission (AIE) character is of particular interest but remains challenging. In this work, we linked two propeller-shaped alkoxyl-substituted tetraphenylethylene (TPE) to the short...

A portable smartphone platform utilizing dual-sensing signals for visual determination of semicarbazide in food samples

“…36,37 For instance, the core of BODIPY, pyrrolopyrrole aza-BODIPY (PPAB), and pyrrolopyrrole cyanine (PPCy) was susceptible to being attacked by nucleophiles such as a base, hydrazine, and organic amine. 38–42 Herein, by virtue of the nucleophilicity of the primary amine group in SEM, our findings indicated that PPCy-1 showed a sensitive response toward SEM through a chromophore reaction (Scheme 1C). This strategy for detecting SEM has the following advantages.…”

Recent advances in aggregation-induced emission (AIE)-based chemosensors for the detection of organic small molecules

“…270 In another example, NIR-emitting fluorophore C43 bearing pyrrolopyrrole aza-BODIPY core was found to show selective detection of diamines and biogenic amines via a dark green-to-yellow colour change, and the turn-on of bright orange fluorescence, due to B–N bond cleavage followed by fast hydrolysis to form smaller conjugated molecules. 271…”

“…fluorescence, due to B-N bond cleavage followed by fast hydrolysis to form smaller conjugated molecules. 271 Amines are generally basic. Therefore, fluorescent amine sensors can be rationally designed to involve deprotonation by basic amine to trigger optical changes.…”

Order–order assembly transition-driven polyamines detection based on iron−sulfur complexes

“…Usually, organic amines are highly toxic, harmful, colorless, and without chromogenic groups, which renders them difficult to be directly differentiated through visual inspection 3 – 5 . Thereinto, polyamines are implicated in diverse functional applications, such as analytical detection 6 , drug development 7 , chemotherapy 8 – 10 , and biological regulation 11 , which makes the determination of polyamines particularly important 12 , 13 , especially in synthetic polyamines detection. For example, the melamine scandal, as an infant-formula milk scandal that results in the hospitalization of tens of thousands of children and even a few deaths 14 , has alarmed the safety of global food chains 15 .…”