Novel Composition of Multifunctional Sunblock from Eisenia bicyclis and Aloe vera Extracts and a Mixed Compound of Titanium Dioxide

Abstract

Purpose: The objective of this study was to develop a novel composition of multifunctional sunblock (NCMFS) by combining extracts from Eisenia bicyclis (E. bicyclis) and Aloe vera (A. vera) with a mixture of micron-and nano-titanium dioxide (TiO 2) powders, which are MP-100 and MPT-136, respectively, characterized by ultraviolet (UV)-blocking properties. Methods: The mixed compound was prepared by combining micron-TiO 2 and nano-TiO 2 particles. The NCMFS was prepared by combining E. bicyclis and A. vera extracts with the mixed compound. The physicochemical properties (particle shape and size) of the mixed compound and UV, infrared (IR), and thermal blocking efficiency of each compound were analyzed. Results: Analysis of the physicochemical properties of the mixed compounds showed that the optimum ratio of mixing MP-100 and MPT-136 was 2.5:7.5. Measurement of sun protection factor (SPF) and protection grade of UV-A (PA) values of A. vera, E. bicyclis, and mixed extracts and NCMFS showed that the NCMFS mixture had the highest values, which were 34.35±0.36 and 34.87±0.36, respectively. Similarly, upon measuring the SPF and PA values, the highest values, 34.39±0.41 and 34.37±0.52, respectively, were measured for NCMFS and compared to the values of each single compound or the mixed compound. In addition, it was found NCMFS has excellent antifine dust adhesion rate and water-resistant properties. Conclusion: Therefore, our results suggested that the NCMFS consisting of the mixture of TiO 2 and E. bicyclis and A. vera extracts has not only UV, IR, and thermal-blocking activity but also antidust protectant and water-resistance properties.

Protective Effects of Lespedeza bicolor Extract on B16/F10 Melanoma Cell Lines Damaged by Lead Acetate, Heavy Metal Compounds

“…따라서, 납독성에 대한 사회적 관심이 집중되면서 독성기전을 비롯하여 효과적인 치료약제나 치료방법에 대한 필요성이 절실히 요구되 고 있다. 특히, 납의 피부독성의 경우 피부세포를 이용한 세포고 사나 DNA 손상에 관한 연구, 납 미세먼지에 의한 피부 및 장기 의 산화적 스트레스나 멜라닌화에 대한 연구 [6,7] 외에 다른 연 구들은 많이 되어 있지 않다 [8,9]. 최근, 납을 비롯한 크롬이나 철, 수은과 같은 몇몇 중금속화합물들은 붕괴될 때 자유라디칼 (free radicals)을 생성함으로써 이들의 독성이 산화적 손상과 관련이 있다고 제기되면서 이들의 독성치료를 산화적 손상 측면 에서 접근하려는 연구가 시도되고 있다 [10].…”