Novel Fluorometric Turn On Detection of Aluminum by Chalcone-Based Chemosensor in Aqueous Phase

Abstract

A novel, 100% water-soluble chalcone based chemosensing receptor {1-[3-(2-Hydroxy-phenyl)-3-oxo-propenyl]-naphthalen-2-yloxy}-acetic acid, L was synthesized and characterized. The receptor L is designed based on the chelation enhanced fluorescence (CHEF) mechanism. The chemosensing properties of L were evaluated by UV-vis and fluorescence spectrometric methods. It exhibits highly selective recognition ability towards aluminum ions in water over other metal ions. The binding stoichiometry of L- Al complex is 2:1 by means of Job's plot and the detection limit is 5.66 × 10 M.

Water-soluble optical sensors: keys to detect aluminium in biological environment

“…6a ). 50 The probe 6 was incorporated with the –COOH acid moiety, which acts as a hard base and provides good water solubility. Fig.…”

A selective bis‐thiophene chalcone‐based spectrofluorimetric sensor for Fe3+

“…This emission property explores the field of chalcone-based fluorescent probes. There are many examples where chalcones have been used as metal ion sensors [23][24][25][26][27][28][29]; however, examples of Fe 3+ sensors are still scarce [30][31][32][33] owing to their ease of interfering with other transition metal ions [34][35][36][37]. Hence, designing a highly selective and sensitive sensor for iron is still challenging.…”

Mass Spectrometric Investigation of Organo-Functionalized Magnetic Nanoparticles Binding Properties toward Chalcones

“…Incorporating various organic residues to chalcone structures may affect an intensified ICT, and thus increased fluorescence, and may be used as a signaling unit in spectral assays, leading to novel sensors working in “on/off mode” under the presence and absence of the specific ions. For instance, chalcones modified with the naphthalenoxy group via formyl linker demonstrated high selectivity towards Al(III) ions, caused by the presence of three oxygen atoms taking part in the ions coordination [ 7 ], while chalcones modified with anthracene and pyridine domains was proved for the selective binding of Pb(II) ions [ 8 ]. Chalcones containing pyrene and pyridine pending groups have been tested for specific Ni(II) binding, which triggered its use as a tool for the investigation of Ni-contamination of biological samples using fluorescent microscopic assays [ 9 ].…”