Novel hybrid electrospun poly(ε‐caprolactone) nanofibers containing green and chemical magnetic iron oxide nanoparticles

Abstract

This study investigates the effects of incorporating green and chemical magnetic iron oxide nanoparticles (GMIONPs and CMIONPs, respectively) into poly (ε-caprolactone) (PCL) nanofibrous membranes on their physicochemical, mechanical, morphological, and functional properties. The study evaluates the physicochemical and optical properties of the nanofibrous membranes using water contact angle (WCA), water vapor permeability (WVP), brightness, color determination, UV-visible and gap energy, and light transmission. The mechanical properties were evaluated using Young's modulus, maximum stress (Ϭ max , MPa), and the strain at break (ε max ), while the morphological properties were evaluated using confocal microscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Functional properties were assessed in terms of antioxidant activity. The results show that incorporating MIONPs significantly affects the properties of the nanofibrous membranes. PCL/GMIONPs membranes exhibit better performance in terms of physicochemical, morphological, and functional properties than PCL/CMIONPs membranes. These findings suggest that PCL/MIONPs nanofibrous membranes could be a promising material for various biomedical applications. The incorporation of different types of magnetic iron oxide nanoparticles into PCL electrospun membranes is an innovative approach that opens up a wide range of potential applications.

Quantifying the Structure and Properties of Nanomagnetic Iron Oxide Particles for Enhanced Functionality through Chemical Synthesis

“…To fabricate PCL/CNMIOPs membranes, solution electrospinning was employed following the methods outlined in a previous study [13]. Briefly, a 10% w/v PCL solution was prepared by dissolving PCL in a chloroform and DMF mixture with a volume ratio of 9:1 at room temperature, forming the electrospinning dope solution.…”

“…This feature holds promise for applications such as targeted drug delivery and tissue regeneration. The incorporation of CNMIOPs into an electrospun PCL matrix can enhance the overall mechanical properties of the scaffold, improving its structural integrity and providing a suitable microenvironment for cell attachment, proliferation, and differentiation [13].…”

Sustainable Nanomagnetism: Investigating the Influence of Green Synthesis and pH on Iron Oxide Nanoparticles for Enhanced Biomedical Applications

“…Among these nanomaterials, iron oxide nanoparticles have gained significant attention due to their exceptional thermal, optical, electronic, and superparamagnetic properties [2]. Iron oxide nanoparticles occur naturally and can be synthesized using different methods, resulting in various iron oxides and oxyhydroxides with distinct crystal structures and iron valence states [3][4][5]. Of particular interest are their magnetic properties, which include saturation magnetization (M s ), coercivity (H c ), remanence (M r ), magnetic diameter, magneto-crystalline anisotropy constant, magnetic relaxation mechanism, and blocking temperature [6].…”