2021
DOI: 10.3390/biom11081186
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Novel Insight of Histamine and Its Receptor Ligands in Glaucoma and Retina Neuroprotection

Abstract: Glaucoma is a multifactorial neuropathy characterized by increased intraocular pressure (IOP), and it is the second leading cause of blindness worldwide after cataracts. Glaucoma combines a group of optic neuropathies characterized by the progressive degeneration of retinal ganglionic cells (RGCs). Increased IOP and short-term IOP fluctuation are two of the most critical risk factors in glaucoma progression. Histamine is a well-characterized neuromodulator that follows a circadian rhythm, regulates IOP and mod… Show more

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References 62 publications
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