SUMMARYThis paper investigates the problem of state observer design for a class of nonlinear uncertain dynamical systems with interval time-varying delay and the one-sided Lipschitz condition. By constructing the novel Lyapunov-Krasovskii functional while utilizing the free-weighting matrices approach, the one-sided Lipschitz condition and the quadratic inner-bounded condition, novel sufficient conditions, which guarantee the observer error converge asymptotically to zero, are established for a class of nonlinear dynamical systems with interval time-varying delay in terms of the linear matrix inequalities. The computing method for observer gain matrix is given. Finally, two examples illustrate the effectiveness of the proposed method.