2012
DOI: 10.1074/jbc.m111.298687
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Novel Mycobacteria Antigen 85 Complex Binding Motif on Fibronectin

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Cited by 46 publications
(46 citation statements)
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“…4 and Table 1) (56)(57)(58). To our knowledge, out of the many Fn binding proteins that have been identified, only a few bind the Hep2-40K region (59)(60)(61)(62).…”
Section: Discussionmentioning
confidence: 99%
“…4 and Table 1) (56)(57)(58). To our knowledge, out of the many Fn binding proteins that have been identified, only a few bind the Hep2-40K region (59)(60)(61)(62).…”
Section: Discussionmentioning
confidence: 99%
“…paratuberculosis like in other mycobacteria (47). Recently, the interaction of Ag85 complex with fibronectin was characterized in molecular detail by measuring dissociation constants and through peptide inhibition assays (36). The investigators identified the 10-amino-acid region within a 40-kDa domain of fibronectin that specifically binds Ag85B.…”
Section: Mycobacterial Proteins Involved In Invasionmentioning
confidence: 99%
“…This 220-kDa host protein consists of 5 well-defined domains of which the 40-kDa domain interacts directly with M. avium subsp. paratuberculosis (36). While M. avium subsp.…”
Section: Host Involvement Enhances Invasionmentioning
confidence: 99%
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“…Streptococcus pneumoniae uses the surface-exposed bacterial protein PspC to facilitate adhesion to the host cell surface by interacting with vitronectin, a host glycoprotein (9). Several mycobacterial proteins that facilitate adhesion to the host epithelial cell membrane, such as fibronectin attachment proteins (FAP), histone-like protein (Hlp), the heparin-binding hemagglutinin (HBHA), and antigen 85, have been characterized (10)(11)(12)(13). Pathogens also take advantage of surface-exposed cytoskeletal proteins for successful adhesion and invasion of epithelial cells.…”
mentioning
confidence: 99%