Novel oxime-palladacycle supported on clay composite as an efficient heterogeneous catalyst for Sonogashira reaction

Copper-free Sonogashira cross-coupling reactions: an overview

“…Remarkably, this supported palladacycle, OxPdCy@clay, exhibited superior catalytic activity in comparison with dimeric oxime-palladacycles. 130 Under the optimal conditions, the Sonogashira coupling reaction of various aryl halides and terminal alkynes was investigated. The reactions of various aryl iodides bearing electron-donating substituents and aryl iodides having electronwithdrawing substituents with aryl acetylenes, 1-octyne, and propargyl alcohol were performed successfully and gave the relevant internal alkynes in very high yields.…”

“…Noticeably, the results demonstrated that the reaction of sterically hindered 2iodocumene and 2-iodotoluene with propargyl alcohol or phenylacetylene occurred in satisfactory yields (Scheme 71). 130 The novel 32-membered macrocyclic dinuclear Pd complex of two aza-crown macrocycles, bearing two pyridine arms, Pd 2 L 2 Cl 4 was synthesized and identied in 2018 by Ghanbari and co-workers. Pd 2 L 2 Cl 4 was used as a moisture/air-stable catalyst in the Sonogashira reaction through a copper-free and phosphine ligand method in dimethyl sulfoxide.…”

“…Remarkably, this supported palladacycle, OxPdCy@clay, exhibited superior catalytic activity in comparison with dimeric oxime-palladacycles. 130 …”

Supramolecular photocatalyst of Palladium (II) Encapsulated within Dendrimer on TiO2 nanoparticles for Photo‐induced Suzuki‐Miyaura and Sonogashira Cross‐Coupling reactions

“…There are many reports of catalytic activity palladium supported on composites as an efficient heterogeneous catalyst in the copper-free Sonogashira cross-coupling reactions. [81][82][83][84][85] Preliminary investigations for the Sonogashira cross-coupling reactions were encouraging and the results are summarized in Table 2 (see the detail of optimizing conditions in supporting information Figure S8).…”

Catalytic α-Hydroarylation of Acrylates and Acrylamides via an Interrupted Hydrodehalogenation Reaction

“…10 This suggests formate may be involved in selectivity determination for versus -hydroarylation and could be consistent with Pathway D but not B or C. Although -selectivity has been observed in intramolecular cyclizations, this has not been previously documented in intermolecular systems. 11 Fourth, we considered a general hydroarylation reaction paradigm (Pathway D). In this "formate-first" pathway, the [Pd II (Ar)(I)] complex can exchange iodide for formate and undergo decarboxylation to furnish a [Pd II (Ar)(H)] complex (step ix).…”