Novel Planar Chip Biosensors for Potentiometric Immunoassay of Acid Phosphatase Activity Based on the Use of Ion Association Complexes as Novel Electroactive Materials

Kamel, Ayman H.; Galal, Hoda R.; Hanna, A. A.

doi:10.1016/s1452-3981(23)08206-8

Cited by 21 publications

(1 citation statement)

References 30 publications

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“…Kamel et al [172] introduced ion association complexes of α-naphthyl acid phosphate (1-NAP) with cetylpyridinium chloride (CP) and iron (II)-4,7-bathophenanthroline [Fe(bphen) 3 ] 2+ as state-of-the-art electroactive materials dispersed in o-nitrophenyloctyl ether (o-NPOE) plasticiser to design an ionometric sensor. The acid phosphatase enzyme (ACP) is present in the lysosomal compartment of the cells and as a non-specific esterase is catalytically active in the hydrolysis of many monoesters of phosphoric acid in an acidic environment.…”

Section: Acid Phosphatase (Acp)mentioning

confidence: 99%

Novel Prostate Cancer Biomarkers: Aetiology, Clinical Performance and Sensing Applications

et al. 2021

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The review initially provides a short introduction to prostate cancer (PCa) incidence, mortality, and diagnostics. Next, the need for novel biomarkers for PCa diagnostics is briefly discussed. The core of the review provides details about PCa aetiology, alternative biomarkers available for PCa diagnostics besides prostate specific antigen and their biosensing. In particular, low molecular mass biomolecules (ions and metabolites) and high molecular mass biomolecules (proteins, RNA, DNA, glycoproteins, enzymes) are discussed, along with clinical performance parameters.

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Section: Acid Phosphatase (Acp)mentioning

confidence: 99%

Novel Prostate Cancer Biomarkers: Aetiology, Clinical Performance and Sensing Applications

et al. 2021

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A dual-signal fluorescent probe for detection of acid phosphatase

Wang

et al. 2021

Anal Bioanal Chem

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Acid phosphatase has become a significant indicator of prognostic and medical diagnosis, and its dysfunction may lead to a series of diseases. A novel dual-signal fluorescence method for acid phosphatase detection based on europium polymer (europiumpyridine dicarboxylicacid-adenine) and pyridoxal phosphate (PLP) was proposed. PLP coordinated with europium polymer via Eu 3+ and P-O bonds, and the fluorescence of europium polymer was quenched due to the photoinduced electron transfer (PET) effect between aldehyde and europium polymer. Upon addition of acid phosphatase, the PLP was transformed to phosphate (Pi) and pyridoxal (PL). The PL was released from the surface of europium polymer, and the blue emission was enhanced due to the formation of internal hemiacetal, while the fluorescence of europium polymer recovered. The blue (PL) and red emission (Eu 3+ ) were positively correlated with acid phosphatase activity; thus the sensitive assay of acid phosphatase was effectively achieved. The two signals were applied to determine the acid phosphatase with limits of detection (LOD) of 0.04 mU/mL and 0.38 mU/mL, and the linear ranges were 0.13-5.00 mU/mL and 1.25-20.00 mU/mL, respectively. The probe can be used to trace the acid phosphatase in biological systems and holds promise for use in clinical diagnosis and early prevention.

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A novel fluorescence biosensor for sensitivity detection of tyrosinase and acid phosphatase based on nitrogen-doped graphene quantum dots

Liu

et al. 2018

Analytica Chimica Acta

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Novel Planar Chip Biosensors for Potentiometric Immunoassay of Acid Phosphatase Activity Based on the Use of Ion Association Complexes as Novel Electroactive Materials

Cited by 21 publications

References 30 publications

Novel Prostate Cancer Biomarkers: Aetiology, Clinical Performance and Sensing Applications

Novel Prostate Cancer Biomarkers: Aetiology, Clinical Performance and Sensing Applications

A dual-signal fluorescent probe for detection of acid phosphatase

A novel fluorescence biosensor for sensitivity detection of tyrosinase and acid phosphatase based on nitrogen-doped graphene quantum dots

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