Novel species of
            <i>Teschovirus B</i>
            comprises at least three distinct evolutionary genotypes

Yang, Tong; Lu, Yuanqing; Zhang, Lingqian; Li, Xinyue; Chang, Yuan Shiun

doi:10.1111/tbed.13400

Cited by 8 publications

(8 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…48 Several novel putative serotypes of PTV have been identified, and a new species, PTV-B, was described in 2019. 46 For PSV-A, a single serotype (PSV1) has been described; 17 serotypes of EV-G are known to infect pigs (G1–G4, G6, G8–G19). 48…”

mentioning

confidence: 99%

Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association

et al. 2021

View full text Add to dashboard Cite

Porcine teschovirus (PTV), sapelovirus (PSV-A), and enterovirus (EV-G) are enteric viruses that can infect pigs and wild boars worldwide. The viruses have been associated with several diseases, primarily gastrointestinal, neurologic, reproductive, and respiratory disorders, but also with subclinical infections. However, for most serotypes, proof of a causal relationship between viral infection and clinical signs is still lacking. In Switzerland, there has been limited investigation of the occurrence of the 3 viruses. We used a modified multiplex reverse-transcription PCR protocol to study the distribution of the viruses in Swiss pigs by testing 363 fecal, brain, and placental or abortion samples from 282 healthy and diseased animals. We did not detect the 3 viruses in 94 placental or abortion samples or in 31 brain samples from healthy pigs. In brain tissue of 81 diseased pigs, we detected 5 PSV-A and 4 EV-G positive samples. In contrast, all 3 viruses were detected at high frequencies in fecal samples of both healthy and diseased pigs. In healthy animals, PTV was detected in 47%, PSV-A in 51%, and EV-G in 70% of the 76 samples; in diseased animals, frequencies in the 81 samples were 54%, 64%, and 68%, respectively. The viruses were detected more frequently in fecal samples from weaned and fattening pigs compared to suckling piglets and sows. Co-detections of all 3 viruses were the most common finding. Based on clinical and pathology data, statistical analysis yielded no evidence for an association of virus detection and disease. Further research is required to determine if pathogenicity is linked to specific serotypes of these viruses.

show abstract

mentioning

confidence: 99%

Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Bei dem im 1-Wochen-▶Tab. 1 Übersicht über die aktuelle Nomenklatur der porzinen Teschoviren (Quellen: [27], [28], [29]). Die früheren Bezeichnungen sind der rechten Spalte zu entnehmen.…”

Section: Anamneseunclassified

“…Stand: Oktober 2021. ▶Table 1 Overview of the current nomenclature of porcine Teschovirus (Sources: [27], [28], [29]). The former termnology is listed in the right column.…”

Section: Anamnesementioning

confidence: 99%

Hinterhandlähmungen bei Mastschweinen im Zusammenhang mit einem neuen Stamm des porzinen Teschovirus A11

Stadler

Junker

Gründl

et al. 2022

Tierarztl Prax Ausg G Grosstiere Nutztiere

View full text Add to dashboard Cite

ZusammenfassungIn einem Schweinemastbetrieb in Süddeutschland konnten über einen Zeitraum von 4 Wochen Hinterhandlähmungen bei 2 Altersgruppen (50 kg sowie 60 kg) beobachtet werden. Die Morbidität bei den beiden Altersgruppen war mit 3,3 % niedrig, der Großteil der betroffenen Tiere musste jedoch aufgrund einer fortschreitenden Paralyse der Hintergliedmaßen euthanasiert werden. Im Rahmen der pathomorphologischen Untersuchung von 2 Mastschweinen konnte eine hochgradige und diffuse lymphohistiozytäre Meningoenzephalomyelitis und Vaskulitis festgestellt werden. Immunhistochemisch wurde in allen Arealen des zentralen Nervensystems und in mehreren Zelltypen (Neuronen, Gliazellen, Endothelzellen, mononukleäre Zellen) Porzines Teschovirus-Antigen nachgewiesen. Die Untersuchung von Rückenmarksproben mittels PCR ergab den Nachweis von Porzinen Teschoviren. Der anschließend durchgeführten phylogenetischen Analyse zufolge wiesen die PCR positiven Proben die höchste Identität (88 % Vollgenomsequenz) zum Porzinen Teschovirus A11 Stamm „Dresden“ auf. Andere differentialdiagnostisch in Frage kommende Pathogene konnten mittels PCR, bakteriologischer Untersuchung und Sequenzierung nicht nachgewiesen werden. In dem Mastbestand traten nach ca. 4 Wochen keine weiteren Fälle von Lähmungserscheinungen mehr auf.

show abstract

“…There are two other genotypes (PTV 15 and PTV 16) belonging to the interspecies recombinants of Teschovirus A and Teschovirus B [11]. PTV infections are prevalent in pigs in China, and almost all known PTV genotypes have been reported [12,13]. Recently, novel strains that are different from the known PTV genotypes in genetic evolutionary relationships have been discovered [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

“…PTV infections are prevalent in pigs in China, and almost all known PTV genotypes have been reported [12,13]. Recently, novel strains that are different from the known PTV genotypes in genetic evolutionary relationships have been discovered [12][13][14]. However, only a short VP1 gene sequence has been obtained for most of the newly discovered PTV strains, which is insufficient to accurately establish the taxonomic statuses of the PTV species and genotypes.…”

Section: Introductionmentioning

confidence: 99%

Identification of a Novel Porcine Teschovirus Subtype 19 within the Species Teschovirus A

Yang,

Lin,

Cui

et al. 2023

Transboundary and Emerging Diseases

Self Cite

View full text Add to dashboard Cite

Porcine teschovirus (PTV) is a member of the genus Teschovirus in the family Picornaviridae. Several novel PTVs in Teschovirus were identified in our previous study. To elucidate the taxonomic status of the species and subtypes, PTV-positive samples were inoculated into porcine kidney (PK-15) and swine testicular (ST) cells. A total of 58 PTV strains were successfully isolated and 21 different VP1 gene sequences were obtained. A phylogenetic analysis of the VP1 gene revealed that these PTV isolates comprised 11 genotypes, including 10 known genotypes (PTV 1–6, PTV 8–9, PTV 11, and Teschovirus B3), and a newly identified genotype. A nearly complete genome sequence of the novel PTV genotype isolate, PTV-SG2, was obtained. The homologies of the nucleotides and amino acids between PTV-SG2 and other PTVs were 69.7%–85.0% and 76.1%–90.4%, respectively. A phylogenetic analysis of the P1, polyprotein, and 3 CD genes revealed that PTV-SG2 belonged to a novel genotype within Teschovirus A, and a genetic divergence analysis of the novel PTV isolate further verified its taxonomic status. Based on the PTV naming convention, the novel PTV genotype identified in the present study was provisionally named PTV 19. Serum neutralization tests indicated that PTV 19 is a serotype-specific and completely different from previously reported PTV serotypes. Therefore, PTV 19 is a novel PTV serogroup. In conclusion, this study identified a PTV genotype and serotype within Teschovirus A.

show abstract

Novel species of Teschovirus B comprises at least three distinct evolutionary genotypes

Cited by 8 publications

References 13 publications

Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association

Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association

Hinterhandlähmungen bei Mastschweinen im Zusammenhang mit einem neuen Stamm des porzinen Teschovirus A11

Identification of a Novel Porcine Teschovirus Subtype 19 within the Species Teschovirus A

Contact Info

Product

Resources

About